Levelanz 250mg Tablets Online At Best Price In Pakistan

GENERIC: Levetiracetam 250mg

MANUFACTURER: Abbott Laboratories Pakistan

QUANTITY

10 Tablets

INDICATION

Levelanz 250mg is prescribed for the treatment of partial onset seizures in adults and adolescents with epilepsy. It is also indicated for myoclonic seizures in patients with juvenile myoclonic epilepsy and primary generalized tonic-clonic seizures. Levelanz serves as an effective adjunctive therapy for patients whose seizures are not adequately controlled with other antiepileptic medications. The medication helps reduce both the frequency and severity of seizure episodes over time. It is suitable for long-term use and is particularly valued for its relatively favorable tolerability.

MECHANISM OF ACTION

Levetiracetam exerts its antiepileptic effect through selective binding to synaptic vesicle protein SV2A in the brain. This interaction modulates neurotransmitter release from presynaptic neurons, effectively dampening the hyperexcitability that leads to seizure activity. The compound also inhibits intraneuronal calcium release and reduces the activity of GABA-negative allosteric modulators, contributing to its broad antiseizure properties without interfering with normal neuronal function.

DOSAGE AND ADMINISTRATION

•      Adults: Initial dose of 250mg twice daily; may be titrated up to 1500mg twice daily.

•      Pediatric dosing is weight-based under physician guidance.

•      Take orally with or without food at consistent times each day.

•      Patients with renal impairment require a dose reduction.

•      Never stop abruptly; always taper under medical supervision.

SIDE EFFECTS

•      Drowsiness and fatigue

•      Dizziness

•      Behavioral changes, including aggression

•      Nasopharyngitis and upper respiratory symptoms

•      Decreased appetite

NOT RECOMMENDED IN

This medication is contraindicated in individuals with known hypersensitivity to levetiracetam or any ingredient in the tablet. Caution is required in patients with renal insufficiency, as dose adjustment is recommended. Levelanz should be used carefully in patients with pre-existing psychiatric conditions, including depression or anxiety. Breastfeeding is not advisable during treatment due to potential drug transfer through breast milk.

DRUG INTERACTIONS

Levelanz 250mg has minimal interaction with the cytochrome P450 enzyme system, reducing the likelihood of significant pharmacokinetic interactions. Co-administration with other anticonvulsants such as phenobarbital or phenytoin may slightly reduce levetiracetam plasma concentrations. Alcohol and CNS depressants may potentiate sedative side effects when combined with Levelanz. Methotrexate co-administration should be approached cautiously as interactions affecting renal clearance have been noted.

STORAGE INSTRUCTIONS

Store in a cool, dry place at temperatures not exceeding 25°C. Protect from light and moisture. Keep the blister pack sealed until use and keep out of reach of children.

WHERE TO BUY

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