TIRZEE 10MG/0.5ML 1S

Quick Answer

TIRZEE 10mg/0.5ml is a prescription-only injectable containing tirzepatide, a dual GIP and GLP-1 receptor agonist manufactured by Getz Pharma. It is indicated for adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise, and is given as a once-weekly subcutaneous injection. The manufacturer's dosing plan starts at 2.5mg weekly and may be escalated by a doctor in 2.5mg steps, of which 10mg/0.5ml is one strength. On Dawa Healthcare pack at around Rs. 9,500 in Pakistan, subject to change and to prescription verification.

Key Takeaways

•     Active Ingredient: Tirzepatide (dual GIP/GLP-1 receptor agonist)

•     Main Use: Adjunct to diet and exercise for adults with insufficiently controlled type 2 diabetes

•     Strength: 10mg/0.5ml

•     Schedule: Once weekly, subcutaneous injection

•     Status: Prescription-only (Rx); prescription upload required at Dawa Healthcare

•     Price: Around Rs. 9,500 at Dawa Healthcare (regular price Rs. 10,000), subject to change

Product Specifications

How TIRZEE 10mg/0.5ml Works

Tirzepatide acts on two gut-hormone receptors, GIP and GLP-1. The manufacturer positions this combined action to help the body release insulin appropriately after meals, slow stomach emptying, and reduce appetite, which together support blood sugar control as part of an overall diabetes care plan that includes diet and exercise.

TIRZEE 10mg/0.5ml Uses

The product is positioned for:

•     Adjunct to diet and exercise in adults with insufficiently controlled type 2 diabetes mellitus

•     Supporting glycaemic (blood sugar) control alongside a doctor-directed treatment plan

•     Convenient once-weekly injection schedule

•     The active ingredient, tirzepatide, is also used internationally (under other brand names) for weight management and other indications; such use should only be considered on a doctor's specific advice

Who Should Use It

Adults with type 2 diabetes who have been specifically prescribed TIRZEE by a doctor as part of a broader treatment plan that includes diet and exercise.

Who Should Avoid It

•     People with type 1 diabetes or diabetic ketoacidosis

•     Anyone with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

•     Anyone with a history of pancreatitis, unless a doctor advises otherwise

•     Anyone with known hypersensitivity to tirzepatide or any excipient

•     Pregnant or breastfeeding women, or anyone planning pregnancy, without specific medical advice

•     Children and adolescents, except where a doctor has specifically prescribed and is monitoring use

Can It Be Used Daily?

No. TIRZEE is designed for once-weekly subcutaneous injection, not daily use. It should be taken on the same day each week, as directed by the prescribing doctor.

How to Take TIRZEE 10mg/0.5ml (Dosage)

TIRZEE 10mg/0.5ml is a higher escalation strength given once weekly by subcutaneous injection, used when a doctor determines a patient needs additional glycaemic or weight-related benefit. Increases beyond earlier strengths should only be made under medical supervision.

General administration guidance from the manufacturer's information:

•     Inject subcutaneously into the abdomen, thigh, or (with assistance) the back of the upper arm; do not inject into a vein or muscle.

•     Rotate the injection site with each weekly dose.

•     Can be taken with or without food, at any time of day, on the same day each week.

•     If a dose is missed, take it within 4 days of the missed dose; if more than 4 days have passed, skip that dose and resume the regular weekly schedule.

•     Do not adjust the strength or frequency without the prescribing doctor's advice.

Side Effects - What to Expect

Common side effects

Nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and abdominal discomfort, particularly during dose changes.

Serious side effects - seek immediate medical advice

•     Severe, persistent abdominal pain (possible pancreatitis)

•     Severe upper abdominal pain, fever, or jaundice (possible gallbladder problems)

•     Signs of an allergic reaction such as facial swelling, difficulty breathing, or rash

•     Signs of hypoglycemia (low blood sugar): dizziness, sweating, confusion, rapid heartbeat, especially if combined with insulin or sulfonylureas

•     A lump or swelling in the neck, hoarseness, or difficulty swallowing (possible thyroid concern)

•     Reduced urination or signs of dehydration, which may indicate kidney complications

•     Vision changes, particularly in people with diabetic eye disease

This list is not exhaustive. If an unexpected or persistent reaction occurs, stop use and seek advice from a qualified healthcare professional.

Boxed Warning

Tirzepatide carries a boxed warning for the risk of thyroid C-cell tumors, based on findings in animal studies; whether this risk applies to humans has not been confirmed. TIRZEE is contraindicated in people with a personal or family history of medullary thyroid carcinoma or MEN 2.

Precautions and Drug Interactions

•     Using TIRZEE together with insulin or sulfonylureas may increase the risk of hypoglycemia; dose adjustment of those medicines may be needed under medical supervision.

•     TIRZEE slows stomach emptying and may alter the absorption of other oral medicines, including oral contraceptives; alternative or additional contraception is generally advised for 4 weeks after starting and after each dose increase.

•     Inform any healthcare provider about TIRZEE use before surgery or procedures requiring anaesthesia, due to a potential increased risk of food or liquid entering the lungs.

•     Monitor for dehydration and kidney function if significant gastrointestinal side effects occur.

•     If you have a medical condition, take other medicines, are pregnant or breastfeeding, or have questions about suitability, consult a qualified healthcare professional before use.

•     Keep out of reach of children.

Storage

Refrigerate at 2-8°C. Do not freeze; discard the pen if it has been frozen. Keep in the original carton to protect from light until time of use. If refrigeration is not available, the pack may be kept at or below 30°C for a limited period as stated on the product labelling. Keep out of reach of children, and dispose of used pens and needles safely as per local sharps-disposal guidance.

TIRZEE 10mg/0.5ml Price in Pakistan

The Dawa Healthcare shows TIRZEE 10mg/0.5ml at around Rs. 9,500 (regular price Rs. 10,000). Prices and availability can change, and dispensing is subject to prescription verification. Buy genuine products from Dawa Healthcare, subject to current availability and delivery coverage in the serviced areas.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. TIRZEE is a prescription-only injectable medicine with a boxed warning; it must only be started, changed, or stopped under the guidance of a qualified doctor. Always follow the product label and your doctor's prescription.

Frequently Asked Questions

What is TIRZEE 10mg/0.5ml used for?

TIRZEE (tirzepatide) 10mg/0.5ml is a prescription injectable medicine indicated for adults with insufficiently controlled type 2 diabetes mellitus, used as an adjunct to diet and exercise. The active ingredient, tirzepatide, is also used internationally for weight management under other brand names; any such use in Pakistan should only follow a doctor's specific advice.

How does tirzepatide work?

Tirzepatide is a dual GIP and GLP-1 receptor agonist. The manufacturer positions it to improve blood sugar control by supporting insulin release, slowing stomach emptying and reducing appetite.

How often is TIRZEE 10mg/0.5ml injected?

TIRZEE is injected once weekly by subcutaneous injection into the abdomen, thigh, or upper arm, on the same day each week, with or without food, as directed by the prescribing doctor.

Can I choose my own TIRZEE dose or switch strengths myself?

No. TIRZEE strengths, including 10mg/0.5ml, are dispensed against a doctor's prescription, and any dose start, change, or discontinuation should be decided by the prescribing doctor, not self-selected.

What are the common side effects of TIRZEE?

Commonly reported effects include nausea, diarrhea, decreased appetite, vomiting, constipation, and abdominal discomfort, particularly during dose changes. A doctor should be informed of any persistent or severe symptoms.

Does TIRZEE have a boxed warning?

Yes. Tirzepatide carries a boxed warning regarding thyroid C-cell tumors observed in animal studies; its relevance to humans has not been confirmed. It is contraindicated in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.

Who should avoid TIRZEE 10mg/0.5ml?

People with type 1 diabetes, a personal or family history of medullary thyroid carcinoma or MEN 2, a history of pancreatitis, known hypersensitivity to tirzepatide, and pregnant or breastfeeding women should avoid TIRZEE unless specifically advised otherwise by a doctor.

How should TIRZEE 10mg/0.5ml be stored?

Refrigerate at 2-8°C and do not freeze. If refrigeration is unavailable, the pen may be kept at or below 30°C for a limited period as stated on the pack; discard if it has been frozen or kept beyond the stated limit. Keep out of reach of children.

Is TIRZEE 10mg/0.5ml available without a prescription in Pakistan?

No. TIRZEE is a prescription-only (Rx) injectable medicine. Dawa Healthcare requires a valid prescription upload before dispensing.

What is the price of TIRZEE 10mg/0.5ml in Pakistan?

The Dawa Healthcare shows TIRZEE 10mg/0.5ml at around Rs. 9,500 (against a regular price of Rs. 10,000), subject to change.