Silagro 50mg Tablets Online At Best Price In Pakistan

Generic: Sildenafil Citrate 50mg

Manufacturer: NabiQasim

Quantity:

4 Tablets

INDICATION

Silagro 50mg Tab is indicated for the treatment of erectile dysfunction in adult men. The 50mg dose is the standard recommended starting dose for most men, offering an effective and well-tolerated balance between efficacy and safety. It is prescribed when a man is unable to achieve or sustain a firm erection during sexual activity. Silagro 50mg restores natural erectile function by improving blood flow to the penis in response to sexual stimulation, enhancing sexual performance and confidence. It is taken on an as-needed basis, ideally 30 to 60 minutes before anticipated sexual activity, and should always be used under the guidance of a qualified physician.

MECHANISM OF ACTION

Sildenafil in Silagro 50mg inhibits the enzyme PDE5, which normally breaks down cGMP in the penile blood vessels. When a man is sexually stimulated, the nervous system releases nitric oxide in the penis, which triggers the production of cGMP. This chemical relaxes the smooth muscle in the blood vessel walls, allowing increased blood flow into the erectile tissue. By stopping PDE5 from breaking down cGMP prematurely, sildenafil prolongs the vasodilatory effect and enables a firm, sustained erection. Without sexual stimulation, sildenafil alone does not produce an erection.

DOSAGE AND ADMINISTRATION

•      Take one 50mg tablet orally with water, 30 to 60 minutes before sexual activity.

•      Do not take more than one tablet in 24 hours.

•      May be taken with or without food; avoid heavy or fatty meals for faster onset.

•      Avoid grapefruit or grapefruit juice before and after dosing.

•      Use only as needed; the dose may be adjusted to 25mg or 100mg by the physician based on response and tolerance.

SIDE EFFECTS

•      Common: Headache, facial flushing, nasal congestion, dizziness, indigestion, transient visual disturbances.

•      Less common: Back pain, muscle aches, blurred vision, mild hypotension, priapism (rare but serious).

NOT RECOMMENDED IN

Silagro 50mg Tab is contraindicated in men taking nitrates for chest pain or heart conditions in any form, as this combination can cause a life-threatening fall in blood pressure. It is not for use in women, children, or men with severe cardiovascular disease, uncontrolled hypertension, or hypotension. It should not be used by men who have had a recent heart attack or stroke. Caution is required in patients with liver disease, retinitis pigmentosa, or anatomical conditions of the penis. Physician evaluation is essential before starting treatment.

DRUG INTERACTIONS

Concurrent use with nitrates or nitric oxide donors is strictly contraindicated. Alpha-blockers can cause pronounced hypotension when combined with sildenafil and should be used with caution and close monitoring. CYP3A4 inhibitors, including ritonavir, ketoconazole, and erythromycin, can significantly elevate sildenafil levels, increasing side effect risk. Grapefruit juice inhibits the CYP3A4 enzyme and must be avoided. Rifampicin and phenytoin are CYP3A4 inducers that can reduce sildenafil's plasma concentration and effectiveness. Alcohol may worsen hypotension and impair erectile function

STORAGE INSTRUCTIONS

Store at room temperature between 15°C and 30°C. Protect from moisture, heat, and direct sunlight. Keep in original packaging. Store out of reach of children and pets. Do not use after the expiry date on the label.

WHERE TO BUY

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