Restiro 60mg Tablets Online At Best Price In Pakistan

Generic: Resmetirom 60mg

Manufacturer: Horizon Pharmaceuticals

Quantity:
10 Tablets

INDICATION

Restiro 60mg Tab is prescribed for adult patients with non-alcoholic steatohepatitis (NASH) accompanied by moderate to advanced liver fibrosis (F2 to F3 stages), as an adjunct to dietary modifications and physical activity. NASH is a serious liver condition driven by excess fat accumulation, chronic inflammation, and progressive scarring of the liver. Restiro targets the metabolic root cause of this disease, working to reduce hepatic fat content, ease liver inflammation, and reverse early-stage fibrosis.

MECHANISM OF ACTION

Resmetirom, the active ingredient in Restiro, selectively binds to the thyroid hormone receptor-beta in the liver. This receptor controls how liver cells manage fat. When activated, it boosts the liver's ability to break down stored fat, reduces the creation of new fat molecules, and lowers triglyceride levels within liver tissue. Think of it as switching on the liver's fat-burning engine. This targeted action reduces the fat overload that causes NASH-related inflammation and scarring, helping restore healthier liver function over time.

DOSAGE AND ADMINISTRATION

●     Recommended dose for patients weighing 100 kg or more: 100 mg once daily, taken orally.

●     Lower doses (60 mg) may apply for patients under 100 kg; follow the physician's guidance.

●     May be taken with or without food.

●     Swallow the tablet whole; do not crush, break, or chew.

●     Administer at the same time daily for best therapeutic results.

SIDE EFFECTS

●     Common: Nausea, diarrhea, abdominal pain, vomiting.

●     Less common: Dizziness, itching, gallbladder-related complications, raised liver enzymes.

NOT RECOMMENDED IN

Restiro 60mg Tab is not recommended in patients with decompensated cirrhosis or those with known allergy to resmetirom. Patients with a history of gallbladder disease require close monitoring during treatment. This medicine is not suitable for use during pregnancy or breastfeeding without the explicit recommendation of a specialist. It should be used with caution in patients with moderate hepatic impairment, and liver function tests should be monitored regularly throughout the course of therapy.

DRUG INTERACTIONS

Resmetirom can interact with statin medications, increasing the risk of muscle damage such as myopathy or rhabdomyolysis. Close monitoring for muscle pain and creatine kinase levels is advised. Co-administration with gemfibrozil or cyclosporine is not recommended due to significant pharmacokinetic interactions. Hepatic transporter may also be affected. Patients should inform their doctor of all current medicines before starting Restiro.

STORAGE INSTRUCTIONS

Store at room temperature (20°C to 25°C). Protect from direct sunlight, heat, and moisture. Keep in the original sealed packaging. Keep away from children. Do not use if the expiry date on the pack has passed.

WHERE TO BUY

Patients across Pakistan can conveniently buy Restiro 60mg Tab online in Pakistan through Dawa Healthcare Pharmacy, a trusted and licensed pharmaceutical platform. For those looking up the Restiro 60mg tablets price in Pakistan, our website provides reliable and up-to-date pricing information. You can order Restiro 60mg Tab online with confidence, and if you are located in Karachi, you can benefit from our same-day delivery service. For all other locations, we deliver through dependable courier services to every corner of Pakistan. Visit any of our multiple Karachi branches or reach us on WhatsApp for personalized support.