NOVOFAX EYE OINT 6GM ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Polymyxin-B + Bacitracin

MANUFACTURER: ISIS Pharmaceuticals

QUANTITY

6gm tube

INDICATION

Novofax Eye Ointment 6GM is a combination antibiotic ophthalmic ointment indicated for the treatment and prevention of superficial bacterial infections of the eye and its adnexa. It is prescribed for bacterial conjunctivitis, blepharitis, corneal abrasions at risk of secondary infection, and as prophylaxis after minor ocular procedures or foreign body removal. The combination provides broad-spectrum coverage by pairing a polypeptide antibiotic effective against gram-negative organisms with one effective against gram-positive organisms.

MECHANISM OF ACTION

Polymyxin B is a polypeptide antibiotic that acts on the bacterial cell membrane. It binds to the phospholipid components of gram-negative bacterial outer membranes, disrupting their structure and increasing membrane permeability. This causes leakage of intracellular contents and bacterial cell death. It is particularly effective against Pseudomonas aeruginosa, E. coli, and Klebsiella species. Bacitracin is a polypeptide antibiotic that inhibits bacterial cell wall synthesis by interfering with the dephosphorylation of C55-isoprenyl pyrophosphate, a lipid carrier essential for peptidoglycan formation. It is primarily active against gram-positive organisms including Staphylococcus aureus and Streptococcus species. Together, the two antibiotics provide complementary coverage across both gram-positive and gram-negative pathogens.

DOSAGE AND ADMINISTRATION

●     Apply a small ribbon (approximately 1cm) of ointment into the lower conjunctival sac of the affected eye(s) every 3 to 4 hours, or 2 to 3 times daily for mild infections

●     For nighttime use: apply once at bedtime to supplement daytime eye drop therapy

●     Treatment duration: 7 to 10 days or as directed by the ophthalmologist

●     Wash hands thoroughly before and after application

●     Gently close the eye and roll the eyeball to distribute the ointment evenly

●     Vision will be temporarily blurred after application due to the ointment base

SIDE EFFECTS

Common:

●     Temporary blurred vision after application

●     Mild burning or stinging upon application

●     Eyelid irritation and mild itching

Less common:

●     Allergic contact dermatitis of the eyelids or periorbital skin

●     Sensitization reactions, particularly to bacitracin, which may preclude future use

●     Overgrowth of non-susceptible organisms including fungi with prolonged therapy

●     Nephrotoxicity with polymyxin B is a systemic concern but negligible with topical ocular use

NOT RECOMMENDED IN

●     Known hypersensitivity to polymyxin B, bacitracin, or any component of the formulation

●     Viral eye infections including herpes simplex keratitis

●     Fungal eye infections

●     Deep penetrating ocular infections where topical therapy alone is insufficient

DRUG INTERACTIONS

Polymyxin B and bacitracin applied topically to the eye have negligible systemic absorption, limiting drug interaction potential. Avoid concurrent use with other nephrotoxic or neurotoxic agents if there is any risk of significant systemic absorption (such as application to large denuded areas). Space other ophthalmic preparations at least 5 to 10 minutes apart, applying drops before ointment when using both.

STORAGE INSTRUCTIONS

Store below 25 degrees Celsius. Keep the tube tightly closed after each use. Avoid touching the nozzle tip to any surface to prevent contamination. Use within 4 weeks of opening. Keep out of reach of children.

WHERE TO BUY

Dawa Healthcare Pharmacy at dawahealthcare.biz carries Novofax Eye Oint 6gm for broad-spectrum bacterial eye infection treatment. Check the Novofax Eye Oint 6gm price in Pakistan and learn about Novofax Eye Oint 6gm uses for conjunctivitis, blepharitis, and nighttime antibacterial eye care on our product page. Multiple Dawa Healthcare branches across Karachi stock ophthalmic ointments under pharmacist supervision. Same-day delivery covers all Karachi service areas, and nationwide courier service extends delivery across Pakistan. WhatsApp ordering at each branch connects you with a pharmacist for eye care guidance.