NIB 5MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Nebivolol Hydrochloride 5mg

MANUFACTURER: Wilsons Pharma (Pvt) Ltd

QUANTITY:

Pack of 14 tablets

INDICATION

Nib 5mg Tab is a third-generation cardioselective beta-1 adrenergic blocker indicated for the treatment of essential hypertension in adults. It is also used in the management of stable chronic heart failure in elderly patients as adjunctive therapy.

MECHANISM OF ACTION

Nebivolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, myocardial contractility, and cardiac output, which collectively lower blood pressure. Unlike older beta-blockers, nebivolol also stimulates endothelial nitric oxide synthase (eNOS), producing vasodilation through NO-mediated mechanisms. This dual action results in effective antihypertensive activity with a favorable hemodynamic profile, causing less bradycardia and peripheral vasoconstriction than non-vasodilating beta-blockers.

DOSAGE AND ADMINISTRATION

•      Hypertension: 5mg once daily, with or without food

•      Heart failure: titrated carefully from lower doses under specialist supervision

•      The same time each day is recommended for consistent blood pressure control

•      Always follow the dosage and monitoring schedule prescribed by your doctor; never stop abruptly

SIDE EFFECTS

Common:

•      Headache and dizziness

•      Fatigue

•      Bradycardia (slow heart rate)

•      Nausea

Less common:

•      Cold extremities due to peripheral vasoconstriction

•      Bronchospasm in asthmatic patients (less likely due to cardioselectivity)

•      Sleep disturbances or nightmares

•      Erectile dysfunction

NOT RECOMMENDED IN

•      Acute decompensated heart failure requiring inotropic support

•      Severe bradycardia or second or third-degree AV block without a pacemaker

•      Severe asthma or COPD with significant bronchospasm

•      Known hypersensitivity to nebivolol or other beta-blockers

DRUG INTERACTIONS

Verapamil and diltiazem combined with nebivolol increase the risk of AV block and bradycardia; avoid concurrent use. CYP2D6 inhibitors such as fluoxetine, paroxetine, and quinidine increase nebivolol plasma levels significantly; dose reduction may be required. Antihypertensives including diuretics and ACE inhibitors have additive blood pressure-lowering effects; monitor closely. Beta-blockers mask tachycardia as a warning sign of hypoglycemia in diabetic patients on insulin.

STORAGE INSTRUCTIONS

Store below 30°C in a dry place away from direct sunlight and moisture. Keep in original blister packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Nib 5mg Tab 14S online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Nib 5mg tab price in Pakistan and learn about Nib 5mg tab uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Nib 5mg tab uses, pricing, and order placement.