NABILOC 2.5MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Bisoprolol Fumarate 2.5mg

MANUFACTURER: Nabi Qasim Industries (Pvt) Ltd

QUANTITY:

14 tablets per pack

INDICATION

Nabiloc 2.5mg Tab is a selective beta-1 adrenergic blocker (cardioselective beta-blocker) used in the management of hypertension, stable angina, and heart failure with reduced ejection fraction. The 2.5mg dose is the standard starting dose in heart failure management, where beta-blocker therapy must be initiated at low doses and gradually up-titrated.

MECHANISM OF ACTION

Bisoprolol selectively blocks beta-1 adrenergic receptors in the heart with minimal effect on beta-2 receptors in the lungs and peripheral vasculature at therapeutic doses. This reduces heart rate, myocardial contractility, and cardiac output, lowering blood pressure and reducing myocardial oxygen demand. In heart failure, chronic sympathetic activation is harmful; bisoprolol's blockade of this pathway prevents beta-adrenoceptor downregulation, reduces arrhythmia risk, and improves cardiac function over time.

DOSAGE AND ADMINISTRATION

•      Heart failure: 1.25mg once daily initially, increasing to 2.5mg after 1 to 2 weeks; titrate slowly toward 10mg/day

•      Hypertension and angina: 5 to 10mg once daily

•      Take in the morning with or without food

•      Never stop abruptly; taper the dose gradually under medical supervision to prevent rebound effects

SIDE EFFECTS

Common:

•      Bradycardia (slow heart rate)

•      Fatigue and dizziness

•      Cold extremities

•      Headache

Less common:

•      Bronchospasm in asthmatic patients (less likely at low doses due to cardioselectivity)

•      Erectile dysfunction

•      Sleep disturbances or nightmares

•      Hypoglycemia masking in diabetic patients on insulin

NOT RECOMMENDED IN

•      Acute heart failure or decompensated heart failure requiring inotropic support

•      Second or third-degree AV block without a pacemaker

•      Severe asthma or COPD with significant bronchospasm

•      Sick sinus syndrome or marked bradycardia

DRUG INTERACTIONS

Verapamil and diltiazem (non-dihydropyridine calcium channel blockers) combined with bisoprolol increase the risk of AV block and bradycardia; generally, avoid. Clonidine: if both are to be stopped, taper bisoprolol first; abrupt clonidine withdrawal with bisoprolol can cause rebound hypertension. Antiarrhythmics (amiodarone) increase bradycardia risk. Insulin and oral antidiabetics: bisoprolol masks tachycardia as a warning sign of hypoglycemia.

STORAGE INSTRUCTIONS

Store below 25°C in a dry place away from direct light. Keep in original blister packaging. Keep out of reach of children.

WHERE TO BUY

You can buy NABILOC 2.5MG TAB online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Nabiloc 2.5mg tab price in Pakistan and learn about Nabiloc 2.5mg tab uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Nabiloc 2.5mg tab uses, pricing, and order placement.