MIBEGA 25MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Mirabegron 25mg

MANUFACTURER: Getz Pharma

QUANTITY:

20 tablets per pack

INDICATION

Mibega 25mg Tab is a beta-3 adrenergic receptor agonist indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults. It is an alternative for patients who cannot tolerate or do not respond adequately to anticholinergic bladder medications.

MECHANISM OF ACTION

Mirabegron selectively activates beta-3 adrenergic receptors in the detrusor muscle of the urinary bladder. Stimulation of these receptors causes relaxation of the detrusor muscle during the filling phase of the micturition cycle, increasing bladder capacity, reducing urgency, and decreasing urinary frequency. Unlike anticholinergic drugs used for OAB, mirabegron does not block muscarinic receptors, so it carries a much lower risk of dry mouth, constipation, and cognitive side effects.

DOSAGE AND ADMINISTRATION

•      Initial dose: 25mg once daily with or without food

•      Dose may be increased to 50mg once daily after 4 to 8 weeks if response is insufficient

•      Swallow tablets whole; do not crush or chew

•      Always follow the dosage prescribed by your doctor; response may take several weeks to be fully apparent

SIDE EFFECTS

Common:

•      Hypertension (elevated blood pressure)

•      Tachycardia (rapid heart rate)

•      Urinary tract infection

•      Nasopharyngitis (common cold)

Less common:

•      Atrial fibrillation

•      Headache and dizziness

•      Elevated liver enzymes

•      Urinary retention (rare)

NOT RECOMMENDED IN

•      Severe uncontrolled hypertension (systolic above 180 mmHg or diastolic above 110 mmHg)

•      End-stage renal disease or severe hepatic impairment without dose adjustment

•      Known hypersensitivity to mirabegron

•      Use with caution in patients with bladder outlet obstruction

DRUG INTERACTIONS

Mirabegron is a moderate CYP2D6 inhibitor; it can increase plasma levels of drugs metabolized by CYP2D6, including metoprolol, desipramine, and flecainide; monitor for toxicity. Digoxin levels may be increased; use the lowest effective digoxin dose and monitor. Warfarin: slight increase in AUC reported; monitor INR at initiation. Avoid with strong CYP3A4 inhibitors in patients with severe renal or hepatic impairment.

STORAGE INSTRUCTIONS

Store below 25°C in a dry place away from direct sunlight. Keep in original packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Mibega 25mg Tab online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Mibega 25mg tab price in Pakistan and learn about Mibega 25mg tab uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Mibega 25mg tab uses, pricing, and order placement.