GVIA-M XR 50/500MG TAB
GVIA-M XR 50/500MG TAB
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Availability:
GVIA-M XR 50/500MG TABLET ONLINE AT BEST PRICE IN PAKISTAN
GENERIC: Sitagliptin 50mg + Metformin 500mg Extended Release
MANUFACTURER: Genix Pharma
QUANTITY:
Pack of 14 tablets
INDICATION
Gvia-M XR 50/500mg Tab is an extended-release combination of sitagliptin and metformin for type 2 diabetes management. The XR formulation allows once-daily dosing with reduced gastrointestinal side effects compared to immediate-release metformin, improving patient adherence.
MECHANISM OF ACTION
Same as other sitagliptin-metformin combinations. The extended-release metformin matrix releases metformin gradually over 12 to 24 hours, reducing peak plasma concentrations and smoothing absorption — which is the main reason for metformin's GI side effects. Sitagliptin is released in a conventional manner.
DOSAGE AND ADMINISTRATION
•     1 to 2 tablets once daily with the evening meal
•     Extended-release tablets must be swallowed whole — do not crush or chew
•     Take with food to optimize metformin absorption
•     Monitor renal function
SIDE EFFECTS
Common:
•     Diarrhoea, nausea (less frequent than with IR metformin)
•     Nasopharyngitis
•     Headache
Less common:
•     Pancreatitis
•     Lactic acidosis (rare)
•     Hypoglycemia with insulin or sulphonylureas
NOT RECOMMENDED IN
•     eGFR below 30ml/min
•     Type 1 diabetes or DKA
•     Hepatic impairment
DRUG INTERACTIONS
Sitagliptin with insulin or sulphonylureas increases hypoglycemia risk; consider dose reduction. Hold metformin 48 hours before iodinated contrast procedures. Avoid alcohol as it raises lactic acidosis risk. ACE inhibitors may slightly increase angioedema risk. Sitagliptin has no significant CYP450 interactions.
STORAGE INSTRUCTIONS
Store below 25°C. Protect from moisture. Keep in original packaging. Store out of reach of children.
WHERE TO BUY
Buy Gvia-M XR 50/500mg Tab online from Dawa Healthcare Pharmacy. Check the Gvia-M XR 50/500mg Tab price in Pakistan and learn about Gvia-M XR 50/500mg Tab uses. Same-day delivery in Karachi. Nationwide delivery through Dawa Healthcare Pharmacy.
SERVICE AREAS: KARACHI
We are available from Monday to Saturday.
Delivery Time:
- Same day delivery is available for orders placed before 8 PM in service areas.
Delivery Charges:
- Delivery charge of 100 PKR on orders over 5000 PKR.
- A delivery charge of 220 PKR applies to orders below 5000 PKR.
NON-SERVICE AREAS: KARACHI
Includes:
1. Baldia
2. Gulshan Hadeed
3. Keemari
4. Port Bin Qasim
5. Highway
ADDITIONAL NOTES FOR OTHER CITIES:
- Currently, we are not offering Cash on Delivery services outside Karachi.
- Only online payments are accepted. Thank you for your cooperation.
- Delivery in cities other than Karachi shall be considered as delivery in Non-Delivery areas.
- For all Non-Delivery areas, Dawa Healthcare is partnering with a third-party logistics provider to provide its services to customers.
- Glass items, Injections, and fridge items cannot be delivered in cities other than Karachi.
Delivery Time:
Delivery will be attempted in 3-5 working days
Delivery Charges(Non-service areas & outside Karachi)
- Orders weighing 0.5 KG or less: Rs. 300
- Orders weighing more than 0.5 kg: Rs. 150 per additional KG