Ranxine 500mg Tablets Online At Best Price In Pakistan

Generic: Ranolazine 500mg

Manufacturer: Horizon Pharmaceuticals

Quantity:

30 tablets per pack

INDICATION

Ranxine 500mg Tab is prescribed for the treatment of chronic stable angina, a condition characterized by recurring chest pain or pressure caused by reduced blood flow to the heart. It is used in patients whose angina is not adequately controlled with other anti-anginal agents. Ranxine provides additional symptom relief by reducing episodes of chest tightness, shortness of breath, and physical limitation caused by angina. It is commonly used as an add-on therapy alongside beta-blockers, calcium channel blockers, or nitrates, offering patients greater exercise tolerance and an improved quality of life without altering heart rate or blood pressure.

MECHANISM OF ACTION

Ranolazine works by blocking a specific sodium channel in the heart called the late sodium current. During angina, this channel stays open too long, letting too much sodium into heart cells, which then causes calcium to build up. That extra calcium makes the heart work harder and reduces blood flow. By blocking this late sodium current, ranolazine reduces the calcium buildup, helps the heart muscle relax properly, and improves blood flow, all without affecting heart rate or blood pressure.

DOSAGE AND ADMINISTRATION

•      Starting dose: 500mg twice daily, taken orally with or without food.

•      Maintenance dose: May be increased to 1000mg twice daily as directed by the physician.

•      Swallow tablets whole; do not crush, chew, or break.

•      Take at the same time each day for consistent benefit.

•      Follow the prescribed dosage and do not self-adjust the dose.

SIDE EFFECTS

•      Common: Dizziness, headache, constipation, nausea.

•      Less common: Blurred vision, vomiting, dry mouth, abdominal discomfort, palpitations.

NOT RECOMMENDED IN

Ranxine 500mg Tab is not recommended in patients with severe hepatic impairment, severe renal impairment, or a history of QT prolongation. It should not be used in individuals with known hypersensitivity to ranolazine or any component of the formulation. Caution is advised in elderly patients and those on concurrent medications that prolong the QT interval. It should not be used during pregnancy or breastfeeding unless specifically directed by a healthcare provider.

DRUG INTERACTIONS

Ranolazine may interact with several medications. Concurrent use with strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, or HIV protease inhibitors can significantly increase ranolazine plasma levels, raising the risk of adverse effects. CYP3A4 inducers like rifampicin, phenytoin, and carbamazepine can reduce its effectiveness. Ranolazine can also increase serum levels of digoxin, simvastatin, and metformin, necessitating dose adjustments.

STORAGE INSTRUCTIONS

Store at room temperature between 15°C and 30°C. Protect from moisture, heat, and direct sunlight. Keep in original packaging. Store out of reach of children and pets. Do not use after the expiry date printed on the pack.

WHERE TO BUY

You can buy Ranxine 500mg Tab online in Pakistan conveniently through Dawa Healthcare Pharmacy, one of the most trusted names in pharmaceutical retail. If you are looking for the Ranxine 500mg tablets price in Pakistan, our platform offers competitive and transparent pricing. Simply order Ranxine 500mg online and enjoy same-day delivery in Karachi, while customers across Pakistan can receive their orders through reliable courier services. Dawa Healthcare operates multiple branches all over Karachi and remains highly responsive on WhatsApp for quick assistance and order placement.