PREDNIVATE CREAM 10GM ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Methylprednisolone Aceponate

MANUFACTURER: Maxitech

QUANTITY

10gm tube

INDICATION

Prednivate Cream 10GM contains methylprednisolone aceponate, a potent topical corticosteroid indicated for the treatment of inflammatory skin conditions responsive to corticosteroid therapy. It is prescribed for atopic dermatitis (eczema), contact dermatitis, seborrheic dermatitis, psoriasis, and other inflammatory dermatoses. Methylprednisolone aceponate is a newer-generation non-halogenated corticosteroid that provides potent anti-inflammatory action with a relatively favorable local safety profile.

MECHANISM OF ACTION

Methylprednisolone aceponate is a diester prodrug that is activated in the skin by esterases to its active metabolite, methylprednisolone 17-propionate. This targeted activation provides high local anti-inflammatory potency while minimizing systemic absorption and side effects. It suppresses inflammation by inhibiting phospholipase A2, reducing prostaglandin, leukotriene, and cytokine production, decreasing capillary permeability, and inhibiting leukocyte infiltration.

DOSAGE AND ADMINISTRATION

●     Apply a thin layer to the affected area once daily

●     Gently rub into the skin until absorbed

●     Treatment duration should not exceed 12 weeks on the body or 4 weeks on the face

●     Use the minimum amount needed to cover the affected area

●     Do not apply under occlusive dressings unless directed by a dermatologist

●     Taper gradually when discontinuing after prolonged use

SIDE EFFECTS

Common:

●     Mild burning or stinging at the application site

●     Skin dryness and itching

●     Mild folliculitis

Less common:

●     Skin thinning (atrophy), telangiectasia, and striae with prolonged use

●     Perioral dermatitis and rosacea-like changes with facial application

●     Hypopigmentation at the application site

●     Adrenal suppression with extensive use over large body surface areas

NOT RECOMMENDED IN

●     Viral skin infections including herpes simplex, varicella, and vaccinia

●     Bacterial or fungal skin infections without concurrent antimicrobial treatment

●     Rosacea and perioral dermatitis

●     Known hypersensitivity to methylprednisolone aceponate or any component

●     Application on open wounds or ulcerated skin

DRUG INTERACTIONS

No significant systemic drug interactions with topical methylprednisolone aceponate. Avoid concurrent use with other topical corticosteroids on the same area. Concurrent use with topical retinoids may increase skin irritation.

STORAGE INSTRUCTIONS

Store below 25 degrees Celsius. Keep tube tightly closed. Protect from light. Keep out of reach of children.

WHERE TO BUY

Dawa Healthcare Pharmacy at dawahealthcare.biz stocks Prednivate Cream 10gm for potent topical anti-inflammatory treatment. Check the Prednivate Cream 10gm price in Pakistan and explore Prednivate Cream 10gm uses for eczema, dermatitis, psoriasis, and inflammatory skin conditions on our product page. Dawa Healthcare branches across Karachi carry dermatological corticosteroids under pharmacist supervision. Same-day delivery covers all Karachi areas, and nationwide courier delivers across Pakistan. WhatsApp ordering at each branch provides pharmacist guidance.