PLAZO 250MG TABLET ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Azithromycin 250mg

MANUFACTURER: Platinum Pharmaceuticals (Pvt) Ltd

QUANTITY:

Pack of 12 tablets

INDICATION

Plazo 250mg Tab is a macrolide antibiotic indicated for mild to moderate bacterial infections caused by susceptible organisms, including community-acquired pneumonia, pharyngitis and tonsillitis, sinusitis, skin and soft tissue infections, otitis media, and urogenital infections caused by Chlamydia trachomatis.

MECHANISM OF ACTION

Azithromycin binds reversibly to the 50S ribosomal subunit of susceptible bacteria, blocking translocation of peptidyl-tRNA and inhibiting RNA-dependent protein synthesis. It is bacteriostatic at standard doses but may be bactericidal at high concentrations against specific organisms. Its unique pharmacokinetic profile includes extensive tissue distribution, a very long tissue half-life of 68 hours, and high intracellular concentrations, allowing once-daily dosing and short 3 to 5-day courses that maintain therapeutic tissue levels for up to 10 days after the final dose.

DOSAGE AND ADMINISTRATION

•      Community-acquired pneumonia: 500mg on day 1, then 250mg once daily on days 2 to 5

•      Pharyngitis, skin infections, sinusitis: 500mg on day 1, then 250mg on days 2 to 5

•      Chlamydia: 1g as a single dose (four 250mg tablets)

•      Always complete the full prescribed course even if symptoms improve

SIDE EFFECTS

Common:

•      Nausea, vomiting, diarrhoea

•      Abdominal pain

•      Headache

•      Dizziness

Less common:

•      QT prolongation and cardiac arrhythmias (rare; risk in at-risk patients)

•      Clostridium difficile-associated diarrhoea with prolonged use

•      Abnormal liver function tests or cholestatic jaundice

•      Hypersensitivity reactions including rash, urticaria, and angioedema

NOT RECOMMENDED IN

•      Known hypersensitivity to azithromycin, erythromycin, or other macrolide antibiotics

•      History of cholestatic jaundice with prior azithromycin use

•      Patients at risk of QT prolongation or taking other QT-prolonging drugs

•      Severe hepatic impairment

DRUG INTERACTIONS

Azithromycin can prolong the QT interval; avoid concurrent use with other QT-prolonging agents including antiarrhythmics, fluoroquinolones, and antipsychotics. Antacids containing aluminium or magnesium reduce azithromycin absorption rate; take at least 1 hour before or 2 hours after antacids. Warfarin anticoagulant effect may be enhanced; monitor INR. Cyclosporine levels may increase; monitor closely.

STORAGE INSTRUCTIONS

Store below 25°C in a dry place away from direct sunlight and moisture. Keep in original blister packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Plazo 250mg Tab 12S online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Plazo 250mg tab price in Pakistan and learn about Plazo 250mg tab uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Plazo 250mg tab uses, pricing, and order placement.