OXA-ONE INJECTION ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Linezolid 600mg (Injection)

MANUFACTURER: Swiss Pharmaceuticals

QUANTITY

As per pack

INDICATION

Oxa-One Injection is an oxazolidinone antibiotic indicated for the treatment of serious infections caused by susceptible gram-positive organisms. It is prescribed for vancomycin-resistant Enterococcus faecium (VRE) bacteremia, nosocomial and community-acquired pneumonia caused by MRSA or penicillin-resistant Streptococcus pneumoniae, and complicated skin and soft tissue infections caused by MRSA. The IV formulation is used when oral administration is not possible or when rapid, reliable drug delivery is needed in critically ill patients.

MECHANISM OF ACTION

Linezolid inhibits bacterial protein synthesis by binding to the 23S rRNA of the 50S ribosomal subunit, preventing the formation of the 70S initiation complex essential for translation. This unique mechanism means cross-resistance with other antibiotic classes does not occur. Linezolid is bacteriostatic against enterococci and staphylococci and bactericidal against most streptococci.

DOSAGE AND ADMINISTRATION

●     Adults: 600mg IV infusion every 12 hours over 30 to 120 minutes

●     Children: 10mg/kg IV every 8 hours, maximum 600mg per dose

●     Duration: 10 to 14 days for skin infections, 14 to 28 days for pneumonia and VRE

●     Do not mix with other IV medications in the same line

●     Must be administered by trained healthcare personnel

●     Monitor complete blood count weekly, especially platelets

SIDE EFFECTS

Common:

●     Diarrhea and nausea

●     Headache

●     Thrombocytopenia, requiring weekly platelet monitoring

●     Infusion site reactions

Less common:

●     Myelosuppression including anemia, leukopenia, and pancytopenia with therapy beyond 2 weeks

●     Peripheral and optic neuropathy with prolonged use

●     Lactic acidosis with extended therapy

●     Serotonin syndrome with concurrent serotonergic agents

NOT RECOMMENDED IN

●     Known hypersensitivity to linezolid or any oxazolidinone

●     Concurrent use with MAOIs or within 2 weeks of MAOI discontinuation

●     Uncontrolled hypertension or pheochromocytoma

●     Concurrent use with serotonergic agents without careful risk assessment

DRUG INTERACTIONS

Linezolid is a weak, reversible MAO inhibitor. Serotonergic drugs (SSRIs, SNRIs, triptans, meperidine, tramadol) may cause serotonin syndrome. Limit tyramine-rich foods during treatment. Sympathomimetics may increase blood pressure.

STORAGE INSTRUCTIONS

Store at room temperature between 15 to 30 degrees Celsius. Protect from light and freezing. Use immediately after removing overwrap. Do not use if the solution is cloudy or contains particles. Keep out of reach of children.

WHERE TO BUY

Dawa Healthcare Pharmacy at dawahealthcare.biz carries Oxa-One Injection for serious gram-positive infections in hospital settings. View the Oxa-One injection price in Pakistan and explore Oxa-One injection uses for MRSA, VRE, and resistant infections on our listing. Dawa Healthcare branches across Karachi stock injectable antibiotics under pharmacist supervision. Same-day delivery covers all Karachi areas, and nationwide courier extends access across Pakistan. WhatsApp ordering at each branch provides prescription verification.