Neurocoline 500mg Tablets Online At Best Price In Pakistan

GENERIC: Citicoline (CDP-Choline) 500mg

MANUFACTURER: Medisure Pharmaceuticals

QUANTITY

10 Tablets

INDICATION

Neurocoline 500mg is indicated as a neuroprotective and nootropic supplement in the management of cognitive impairment, cerebrovascular disorders, and neurological rehabilitation. It is widely prescribed as an adjunct in the treatment of acute ischemic stroke, traumatic brain injury, and age-related cognitive decline. Citicoline supports brain cell membrane synthesis, reduces neuronal damage, and promotes neurological recovery after ischemic events.

MECHANISM OF ACTION

Citicoline (cytidine-5-diphosphocholine) is a natural substance in the body that helps make phosphatidylcholine, an important part of brain cell membranes. When taken orally, it breaks down into cytidine and choline, which are absorbed and then recombined in the brain. Citicoline helps repair damaged brain cells, reduces harmful fatty acid release after brain injury, and boosts acetylcholine production, a neurotransmitter important for memory and thinking. Together, these effects protect the brain and support healthy brain function.

DOSAGE AND ADMINISTRATION

•      Adults: 500–1000mg once or twice daily as prescribed by a physician.

•      For acute stroke: administer within 24 hours of onset as directed.

•      Take with or without food; swallow whole with water.

•      For cognitive maintenance: continue for 3–6 months with regular reassessment.

•      Dose adjustments are not typically required for renal or hepatic impairment.

SIDE EFFECTS

•      Generally very well tolerated

•      Mild nausea or headache

•      Insomnia if taken too late in the day

•      Mild gastrointestinal discomfort

•      Rare: allergic reactions, hypo- or hypertension at high doses

NOT RECOMMENDED IN

Neurocoline 500mg is contraindicated in patients with known hypersensitivity to citicoline or any excipient. It should be used with caution in patients with hypertonia (increased muscle tone) as citicoline may worsen this condition. Not recommended in patients with hereditary hypertonia or dystonia without neurologist evaluation. Safety during pregnancy and lactation has not been adequately established; physician guidance is essential. Patients with uncontrolled hypertension should be monitored during citicoline therapy due to its cholinergic effects on vascular tone.

DRUG INTERACTIONS

Citicoline may enhance the effects of levodopa in Parkinson's disease management; dose adjustments of levodopa may be necessary to avoid dyskinesia. It may potentiate the action of meclofenoxate and should be used cautiously in patients receiving cholinergic agents. Citicoline does not have known significant pharmacokinetic interactions with common antihypertensives, statins, or antidepressants.

STORAGE INSTRUCTIONS

Store below 25°C in a cool, dry place away from light and moisture. Keep in original packaging and out of reach of children. Do not use after the expiry date.

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