MEDISOPT DROP ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Dorzolamide 2% + Timolol 0.5%

MANUFACTURER: Medipak Limited

QUANTITY

5ml eye drops

INDICATION

Medisopt Drop is a fixed-dose combination ophthalmic solution indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers alone. It provides the convenience of a single bottle containing two complementary IOP-lowering agents to prevent progressive optic nerve damage and visual field loss.

MECHANISM OF ACTION

Dorzolamide is a topical carbonic anhydrase inhibitor that reduces aqueous humor secretion by approximately 40 to 60% by inhibiting carbonic anhydrase II in the ciliary body. Timolol is a non-selective beta-adrenergic antagonist that further decreases aqueous humor production by blocking beta-2 receptors. The combination provides additive IOP reduction greater than either agent alone, typically lowering IOP by 7 to 10 mmHg.

DOSAGE AND ADMINISTRATION

·        Instill 1 drop in the affected eye(s) twice daily, approximately 12 hours apart

·        Apply gentle nasolacrimal occlusion for 2 minutes after instillation to reduce systemic absorption

·        Remove contact lenses before instillation and wait 15 minutes before reinserting

·        If using additional eye drops, space applications at least 10 minutes apart

·        Do not alter the dosing frequency without consulting your ophthalmologist

·        Continue using even if you feel well, as glaucoma often has no noticeable symptoms

SIDE EFFECTS

Common:

·        Burning and stinging sensation upon instillation

·        Bitter or unusual taste in the mouth due to nasolacrimal drainage

·        Blurred vision immediately after application

·        Mild eye redness and superficial punctate keratitis

Less common:

·        Systemic beta-blocker effects including bradycardia, hypotension, and bronchospasm

·        Fatigue, dizziness, and headache

·        Corneal edema in patients with compromised corneal endothelium

·        Allergic reactions including eyelid dermatitis

NOT RECOMMENDED IN

Bronchial asthma, severe COPD, or history of bronchospasm

Sinus bradycardia, second or third-degree AV block, or overt cardiac failure

Known hypersensitivity to sulfonamides, beta-blockers, or any component

Severe renal impairment (creatinine clearance below 30ml/min)

DRUG INTERACTIONS

Concurrent use with systemic beta-blockers may produce additive cardiac effects. Oral carbonic anhydrase inhibitors may increase systemic side effects. Calcium channel blockers may potentiate hypotension. CYP2D6 inhibitors may increase systemic timolol exposure.

STORAGE INSTRUCTIONS

Store at room temperature between 15 to 25 degrees Celsius. Protect from light. Do not freeze. Discard 4 weeks after first opening. Keep the bottle tightly closed. Keep out of reach of children.

WHERE TO BUY

Dawa Healthcare Pharmacy at dawahealthcare.biz is Pakistan's trusted source to buy Medisopt Drop online for glaucoma and ocular hypertension management. Find the Medisopt Drop price in Pakistan and learn about Medisopt Drop uses for lowering eye pressure and protecting vision on our listing. Dawa Healthcare maintains multiple branches across Karachi ensuring proper storage for ophthalmic medications under pharmacist supervision. Same-day delivery is available in all Karachi service areas, and nationwide courier service reaches patients across Pakistan. WhatsApp ordering at each branch provides direct pharmacist assistance.