Lipitor 40mg Tablets Online At Best Price In Pakistan

GENERIC: Atorvastatin Calcium 40mg

MANUFACTURER: Pfizer Pakistan

QUANTITY

10 Tablets

INDICATION

Lipitor 40mg is indicated for the reduction of elevated total cholesterol, LDL cholesterol, and triglycerides in patients with primary hypercholesterolemia and mixed dyslipidemia. It is widely prescribed as part of a comprehensive cardiovascular risk reduction strategy in adults and children above 10 years. Lipitor significantly lowers the risk of major cardiovascular events, including myocardial infarction, stroke, and arterial revascularization procedures. It is also used in patients with type 2 diabetes who have additional cardiovascular risk factors.

MECHANISM OF ACTION

Atorvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme responsible for cholesterol biosynthesis in the liver. By blocking this enzyme, atorvastatin reduces hepatic cholesterol production, which in turn upregulates LDL receptor expression on liver cells. This results in increased clearance of LDL particles from the bloodstream, significantly lowering plasma LDL levels. Atorvastatin also has modest effects on reducing triglycerides and raising HDL cholesterol.

DOSAGE AND ADMINISTRATION

•      Adults: 10–80mg once daily; the 40mg dose is typically a maintenance or intensification dose.

•      Can be administered at any time of day with or without food.

•      Swallow whole; do not crush or chew.

•      Dose adjustments based on lipid targets and tolerability.

•      Use the lowest effective dose to minimize side effects.

SIDE EFFECTS

•      Muscle pain or myalgia

•      Headache

•      Nausea and gastrointestinal discomfort

•      Elevated liver enzymes

NOT RECOMMENDED IN

Lipitor 40mg is contraindicated in patients with active liver disease or unexplained persistent elevations in serum transaminases. It should not be used during pregnancy or breastfeeding due to the potential risk to the fetus. Patients with myopathy or those at high risk of rhabdomyolysis should avoid statins.

DRUG INTERACTIONS

Atorvastatin is metabolized primarily by CYP3A4, and concurrent use of CYP3A4 inhibitors such as clarithromycin, itraconazole, or HIV protease inhibitors can significantly increase atorvastatin plasma levels, raising the risk of myopathy. Fibrates, particularly gemfibrozil, combined with atorvastatin, increase the risk of myopathy and rhabdomyolysis. Cyclosporine and niacin can also elevate statin exposure. Antacids may reduce atorvastatin absorption when taken simultaneously.

STORAGE INSTRUCTIONS

Store at temperatures below 25°C in a dry place away from direct light and moisture. Keep in original blister packaging and out of reach of children.

WHERE TO BUY

Lipitor 40mg Tab is available online in Pakistan through Dawa Healthcare Pharmacy, your trusted source for branded and generic medications. Customers looking to check Lipitor 40mg tablets price in Pakistan or order Lipitor 40mg Tab online can do so easily through a simple and user-friendly platform. Dawa Healthcare ensures reliable nationwide delivery through courier services across Pakistan, along with same-day delivery available in Karachi. Every product is maintained with strict quality assurance and proper storage conditions to ensure authenticity and effectiveness.