LACOLEP 150MG 14S
LACOLEP 150MG 14S
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LACOLEP 150MG ONLINE AT BEST PRICE IN PAKISTAN
GENERIC: Lacosamide 150mg
MANUFACTURER: Hilton Pharma
QUANTITY
14 tablets
INDICATION
Lacolep 150mg is an antiepileptic medication indicated as monotherapy or adjunctive therapy for the treatment of partial-onset (focal) seizures with or without secondary generalization in adults and adolescents aged 16 years and above with epilepsy.
MECHANISM OF ACTION
Lacosamide selectively enhances the slow inactivation of voltage-gated sodium channels, stabilizing hyperexcitable neuronal membranes without affecting normal neuronal firing. This distinguishes it from traditional sodium channel blockers like carbamazepine and phenytoin, which primarily affect fast inactivation. By targeting slow inactivation, lacosamide reduces the availability of sodium channels for repetitive firing during seizure activity while preserving normal brain function.
DOSAGE AND ADMINISTRATION
● Adults: starting dose 50mg twice daily, titrated by 50mg twice daily at weekly intervals
● Recommended maintenance: 150 to 200mg twice daily
● Maximum: 400mg daily (200mg twice daily)
● Swallow tablets whole with water
● May be taken with or without food
● Do not discontinue abruptly; taper over at least one week
SIDE EFFECTS
Common:
● Dizziness
● Headache
● Nausea
● Diplopia (double vision)
Less common:
● PR interval prolongation on ECG
● Ataxia or balance disturbance
● Suicidal ideation, as with all antiepileptics
● Multiorgan hypersensitivity reaction in rare cases
NOT RECOMMENDED IN
● Known hypersensitivity to lacosamide
● Second or third degree AV block
● Severe hepatic impairment
● Concurrent use with other PR-prolonging drugs requires caution
DRUG INTERACTIONS
CYP2C19 inhibitors such as fluconazole and omeprazole may moderately increase lacosamide levels. PR-prolonging drugs including beta-blockers and calcium channel blockers increase the risk of cardiac conduction abnormalities. Strong enzyme inducers like rifampicin, carbamazepine, and phenytoin may reduce lacosamide plasma levels.
STORAGE INSTRUCTIONS
Store below 25 degrees Celsius. Protect from moisture. Keep in original packaging. Keep out of reach of children.
WHERE TO BUY
Dawa Healthcare Pharmacy at dawahealthcare.biz is the trusted destination to buy Lacolep 150mg online. The Lacolep 150mg uses and the Lacolep 150mg price in Pakistan are displayed on our listing. Multiple Karachi branches with same-day delivery and nationwide courier service across Pakistan. WhatsApp ordering at each branch provides direct pharmacist support.
SERVICE AREAS: KARACHI
We deliver Monday to Sunday across Karachi.
Delivery Time:
- 99 Minute Delivery: Available for orders within 10 km of our branches, from 9:00 AM to 12:00 AM.
-
Same Day Delivery: Available for locations beyond 10 km, with an 8:00 PM order cut off.
Delivery Charges: - Free Delivery on orders over 10000 PKR
- Delivery charge of 100 PKR on orders over 5000 PKR.
- A delivery charge of 200 PKR applies to orders below 5000 PKR.
NON-SERVICE AREAS: KARACHI
Includes:
1. Baldia
2. Gulshan Hadeed
3. Keemari
4. Port Bin Qasim
5. Highway
6. Orangi Town
7. Memon Goth
ADDITIONAL NOTES FOR OTHER CITIES:
- Currently, we are not offering Cash on Delivery services outside Karachi.
- Only online payments are accepted. Thank you for your cooperation.
- Delivery in cities other than Karachi shall be considered as delivery in Non-Delivery areas.
- For all Non-Delivery areas, Dawa Healthcare is partnering with a third-party logistics provider to provide its services to customers.
- Glass items, Injections, and fridge items cannot be delivered in cities other than Karachi.
Delivery Time:
Delivery will be attempted in 3-5 working days
Delivery Charges:
- Orders weighing 0.5kg or less: Rs. 450
- Orders weighing more than 0.5kg: Rs. 200 per additional kg