Avsar Plus 160/5/25mg Tablet (Amlodipine 5mg + Valsartan 160mg + Hydrochlorothiazide 25mg)

Quick Answer: Avsar Plus 160/5/25mg Tablet is a prescription blood pressure medicine by PharmEvo that combines amlodipine 5 mg, valsartan 160 mg and hydrochlorothiazide 25 mg in one tablet taken once daily. It is used when blood pressure is not controlled on two medicines. A strip costs Rs. 115.90 at Dawa Healthcare, 10% off Rs. 128.70. Order online for 99-minute or same-day delivery in Karachi.

Key Takeaways

•       Active Ingredients: amlodipine 5 mg + valsartan 160 mg + hydrochlorothiazide (HCTZ) 25 mg

•       Use: essential hypertension in adults not controlled on 2 blood pressure medicines; not for first-line treatment

•       Dose: one tablet once daily, preferably in the morning

•       Common Side Effects: dizziness, headache, ankle swelling, low potassium, frequent urination and indigestion

•       Pregnancy: must not be used; stop as soon as pregnancy is detected

•       Prescription: required

•       Price: Rs. 115.90 per strip (10% off Rs. 128.70); order online for 99-minute or same-day Karachi delivery

📋 Product Specifications

How Avsar Plus 160/5/25mg Tablet Works

Avsar Plus lowers blood pressure through 3 separate mechanisms. Amlodipine relaxes blood vessel walls, valsartan blocks angiotensin II so vessels stay open, and hydrochlorothiazide helps the kidneys remove extra salt and water. Valsartan also tends to balance the potassium loss caused by hydrochlorothiazide.

Avsar Plus 160/5/25mg Tablet Uses

•       Hypertension: treats essential high blood pressure in adults

•       Add-On or Switch Therapy: for patients not controlled on any 2 of: calcium channel blockers, ARBs and diuretics

•       Replacement Therapy: replaces 3 separate tablets at the same doses with one daily tablet

Who Should Use Avsar Plus 160/5/25mg Tablet

Adults with high blood pressure that is not controlled on two medicines, whose doctor has prescribed this exact strength. PharmEvo states that Avsar Plus is not for the initial treatment of hypertension. High blood pressure is common and often uncontrolled: the WHO estimates 1.28 billion adults aged 30-79 have hypertension and only about 1 in 5 have it under control, and the National Health Survey of Pakistan (1990-94) found it in 17.9% of adults and one in three people over 45.

🚫 Who Should Avoid It

•       Pregnancy: contraindicated in the second and third trimesters and not recommended in the first

•       Allergy: to valsartan, amlodipine, hydrochlorothiazide, sulphonamides or dihydropyridines

•       Kidney or Liver Disease: severe kidney impairment (CrCl below 30 mL/min), no urine output, dialysis, or any level of liver impairment

•       Electrolyte Problems: persistent low potassium or sodium, high calcium, or symptomatic gout

•       Heart Conditions: severe low blood pressure, shock, outflow obstruction such as severe aortic stenosis, or unstable heart failure after a heart attack

•       Aliskiren: do not combine in people with diabetes or reduced kidney function

💊 How to Take Avsar Plus 160/5/25mg Tablet (Dosage)

1.     Take One Tablet Daily: Take one Avsar Plus 160/5/25mg Tablet once a day, exactly as your doctor prescribed.

2.     Keep the Same Time: Take it at the same time each day, preferably in the morning.

3.     With or Without Food: Swallow the tablet whole with a glass of water, with or without food.

4.     Check Your Blood Pressure: Measure your blood pressure at home and keep a log for your doctor.

5.     Do Not Stop Suddenly: Keep taking it even when you feel well; stop or change the dose only on your doctor's advice.

The dose may be increased after 2 weeks, and the full effect appears about 2 weeks after reaching the maximum dose of 320/10/25 mg. If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed one; never take two tablets together.

⚠️ Side Effects

•       Common: dizziness, headache, ankle swelling, low blood pressure, low potassium, frequent urination, indigestion and tiredness

•       Less Common: raised uric acid or blood sugar, low sodium, sensitivity to sunlight, muscle cramps

•       Seek Help Immediately: swelling of the face, lips or throat; sudden eye pain or blurred vision (a rare glaucoma reaction to hydrochlorothiazide); fainting or severe weakness

🛡️ Precautions and Drug Interactions

Your doctor should check potassium, sodium, kidney function and uric acid regularly. Diabetes medicines may need adjusting because hydrochlorothiazide can raise blood sugar. Tell your doctor if you take potassium supplements or salt substitutes, NSAID painkillers, lithium, digoxin, other RAS blockers (ACE inhibitors, aliskiren), clarithromycin, ketoconazole or simvastatin above 20 mg daily. Avoid grapefruit juice, use sun protection, and take care when driving if you feel dizzy.

💊 All Avsar Plus Strengths at Dawa Healthcare

Avsar Plus comes in 5 strengths. The maximum recommended dose is 320/10/25 mg once daily.

For patients who do not need a diuretic, Avsar (amlodipine + valsartan) comes in 5/80 mg, 5/160 mg and 10/160 mg, such as Avsar 5mg+160mg.

🏠 Storage

Store below 30°C, protected from heat, light and moisture, and keep out of reach of children (PharmEvo prescribing information).

💰 Avsar Plus 160/5/25mg Tablet Price in Pakistan

Avsar Plus 160/5/25mg Tablet costs Rs. 115.90 per strip at Dawa Healthcare as of 1 October 2026 (10% off Rs. 128.70). Order online for 99-minute or same-day delivery in Karachi, or courier delivery to other cities in 3-5 working days. See the Shipping Policy and Refund & Return Policy for charges and terms.

Avsar Plus 160/5/25mg Tablet vs Similar Options

Avsar Plus 160/5/25mg costs Rs. 115.90 per strip at Dawa Healthcare. Exforge HCT is the original Novartis brand of this combination, and Avsar Plus is PharmEvo's Pakistani brand. Switch brands only with your doctor or pharmacist. Explore the Medicine category.

Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Take this medicine only as prescribed, and consult your doctor or pharmacist before starting, stopping or changing any treatment.

❓ Frequently Asked Questions

What is Avsar Plus 160/5/25mg Tablet used for?

It treats high blood pressure in adults whose blood pressure is not controlled on two medicines. It combines amlodipine 5 mg, valsartan 160 mg and hydrochlorothiazide 25 mg in one tablet.

Where can I buy Avsar Plus 160/5/25mg Tablet in Pakistan?

Order genuine Avsar Plus 160/5/25mg Tablet online from Dawa Healthcare  Rs. 115.90 per strip as of 1 October 2026 (10% off Rs. 128.70). Prices can change without notice.

Is a prescription required to buy Avsar Plus 160/5/25mg Tablet?

Yes. It is a prescription-only medicine. Upload your prescription when you order at dawahealthcare.biz, or use the Arrange For Me service.

What is the dose of Avsar Plus 160/5/25mg Tablet?

One tablet once daily, preferably in the morning, with or without food. The maximum recommended Avsar Plus dose is 320/10/25 mg per day.

What are the side effects of Avsar Plus 160/5/25mg Tablet?

Common side effects include dizziness, headache, ankle swelling, low potassium, frequent urination and indigestion. Seek urgent care for face or throat swelling or sudden eye pain.

Can I take Avsar Plus 160/5/25mg Tablet during pregnancy?

No. It is contraindicated in the second and third trimesters and not recommended in the first. Contact your doctor as soon as you know you are pregnant.

What is the difference between Avsar and Avsar Plus?

Avsar contains amlodipine and valsartan. Avsar Plus adds hydrochlorothiazide, a diuretic, for patients who need a third blood pressure medicine.

Why does Avsar Plus 160/5/25mg Tablet make me urinate more?

Hydrochlorothiazide is a diuretic that helps the kidneys remove extra salt and water. Taking the tablet in the morning helps avoid waking at night to urinate.

Does Dawa Healthcare deliver Avsar Plus 160/5/25mg Tablet outside Karachi?

Yes. Order online and it ships by courier in 3-5 working days, online payment only, at Rs. 450 up to 0.5 kg plus Rs. 200 per extra kg. Karachi orders get 99-minute or same-day delivery.