{"product_id":"zexa-10mg-tab-56s","title":"ZEXA 10MG TAB 56S","description":"\u003ch1\u003e\u003cspan style=\"mso-ansi-language: EN-US;\"\u003eZexa 10mg Tablets Online At Best Price In Pakistan\u003c\/span\u003e\u003c\/h1\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eGENERIC: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eMemantine HCl 10mg\u003cb\u003e\u003c\/b\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eMANUFACTURER: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eA'raf Pharmaceuticals\u003cb\u003e\u003c\/b\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eQUANTITY: \u003c\/span\u003e\u003c\/b\u003e\u003c\/h3\u003e\n\u003ch3\u003e\u003cspan lang=\"EN-GB\"\u003e56 Tablets per pack\u003cb\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eINDICATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eZexa 10mg Tab is indicated for the treatment of moderate to severe dementia associated with Alzheimer's disease in adults. It is used to improve or stabilize cognitive symptoms, including memory, attention, reasoning, language, and the ability to perform daily activities. It may also reduce the behavioral disturbances that frequently accompany Alzheimer's disease, including agitation and aggression. Memantine does not cure or halt the underlying disease process but provides meaningful symptomatic benefit and can slow the rate of functional decline in patients with established moderate to severe Alzheimer's disease. The 56-tablet pack supports a full month of twice-daily therapy.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eMECHANISM OF ACTION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal; margin: 12.0pt 0in 12.0pt 0in;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eMemantine is a low-to-moderate affinity, uncompetitive NMDA receptor antagonist used in Alzheimer’s disease that attenuates pathological glutamate-mediated receptor overactivation. This persistent overactivity drives excessive calcium influx, leading to excitotoxic neuronal injury. Memantine blocks the receptor in a voltage-dependent manner, preferentially during abnormal activation, while rapidly disengaging under physiological conditions. This preserves normal synaptic transmission. By reducing excitotoxicity and optimizing glutamatergic signaling, memantine supports cognitive function.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDOSAGE AND ADMINISTRATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eStarting dose: 5mg once daily in week one.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eWeek two: 5mg twice daily (10mg total daily).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eWeek three: 15mg daily (5mg in the morning, 10mg in the evening).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eMaintenance dose from week four: 10mg twice daily (20mg total daily).\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSIDE EFFECTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eCommon: Dizziness, headache, constipation, somnolence, hypertension.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eLess common: Fatigue, pain, hallucinations, confusion, vomiting, urinary incontinence.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eNOT RECOMMENDED IN\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eZexa 10mg Tab is contraindicated in patients with known hypersensitivity to memantine or any component of the formulation. Use with caution in patients with severe renal impairment (dose reduction required in moderate renal impairment), severe hepatic impairment, epilepsy, and conditions that raise urinary pH, such as renal tubular acidosis or severe urinary tract infections, as alkaline urine reduces memantine renal excretion and may increase plasma concentrations. Not recommended for use in children for Alzheimer's disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDRUG INTERACTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eNMDA antagonists, including amantadine, ketamine, and dextromethorphan, should be co-administered with caution as additive NMDA blockade may produce adverse effects, including psychosis and confusion. Alkalinizing agents, including carbonic anhydrase inhibitors and sodium bicarbonate, increase urinary pH and reduce memantine clearance, potentially leading to toxicity. Drugs excreted by the same renal tubular cation transport system, including cimetidine, ranitidine, procainamide, quinidine, and nicotine, may have altered plasma concentrations when co-administered. L-DOPA and dopaminergic agonists may have enhanced effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSTORAGE INSTRUCTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eStore at room temperature between 15°C and 30°C. Protect from moisture and direct light. Keep in original blister packaging. Store out of reach of children. Do not use after the expiry date on the pack.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eWHERE TO BUY\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eDawa Healthcare provides families and caregivers with a reliable online source to buy Zexa 10mg Tab 56s in Pakistan at dawahealthcare.biz. We understand the importance of uninterrupted access to dementia medications, which is why we offer same-day delivery in Karachi and fast courier dispatch nationwide to all cities across Pakistan. Our WhatsApp number connects you directly to our team for ordering and advice. All Dawa Healthcare Pharmacy branches across Karachi carry commonly prescribed neurological medications for walk-in customers. The Zexa 10mg tablets 56s price in Pakistan is listed on our website alongside information on Zexa 10mg tab uses.\u003c\/span\u003e\u003c\/p\u003e","brand":"Dawa Healthcare","offers":[{"title":"Pack","offer_id":51629458817307,"sku":"15019","price":3362.1,"currency_code":"PKR","in_stock":true},{"title":"Strip","offer_id":51629458850075,"sku":"15019-1","price":480.3,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/placeholder_720x_e2630a98-d543-4496-aba4-cb4b3e0dcfed.jpg?v=1768418416","url":"https:\/\/dawahealthcare.biz\/products\/zexa-10mg-tab-56s","provider":"Dawa Healthcare","version":"1.0","type":"link"}