{"product_id":"xenglu-met-5mg-500mg-tab-14s","title":"XENGLU MET 5MG+500MG TAB 14S","description":"\u003ch1\u003e\u003cspan style=\"mso-ansi-language: EN-US;\"\u003eXenglu Met 5+500mg Tablets Online At Best Price In Pakistan\u003c\/span\u003e\u003c\/h1\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eGENERIC: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eEmpagliflozin 5mg+Metformin HCl 500mg\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003ca name=\"_81hsc9z1tiq6\"\u003e\u003c\/a\u003e\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eMANUFACTURER: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eHilton Pharma\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003ca name=\"_mcpzjtkskt96\"\u003e\u003c\/a\u003e\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eQUANTITY: \u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003ca name=\"_nfui37bxrozn\"\u003e\u003c\/a\u003e\u003cspan lang=\"EN-GB\"\u003e14 Tablets per pack\u003c\/span\u003e\u003cb\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 18.0pt; line-height: 115%;\"\u003e\u003c\/span\u003e\u003c\/b\u003e\n\u003c\/h3\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eINDICATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eXenglu Met 5mg+500mg Tab is a lower-strength fixed-dose combination of empagliflozin and metformin indicated for the management of type 2 diabetes mellitus in adults as an adjunct to diet and exercise. This initiation-friendly formulation is suitable for patients transitioning from metformin monotherapy to dual therapy who require a gradual approach to minimize gastrointestinal intolerance, patients with mild to moderate hyperglycemia not requiring higher metformin doses at treatment initiation, and those beginning combination SGLT2 inhibitor and metformin therapy in a stepwise manner. The lower doses of both components make this the preferred starting point for many patients initiating dual therapy, with escalation to higher-strength combinations as tolerated and as glycemic targets require.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eMECHANISM OF ACTION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal; margin: 12.0pt 0in 12.0pt 0in;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eEmpagliflozin 12.5 mg inhibits SGLT2 in the kidneys, reducing glucose and sodium reabsorption and promoting urinary glucose excretion, which lowers both fasting and postprandial blood sugar without increasing insulin release, thus carrying a low risk of hypoglycemia. Its mild diuretic effect also helps reduce blood pressure and provides cardiovascular and renal protection. Metformin 1000 mg works by activating AMPK, significantly decreasing hepatic glucose production, and improving insulin sensitivity in peripheral tissues. Together, they offer complementary and synergistic glycemic control by targeting both renal glucose elimination and hepatic glucose overproduction.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDOSAGE AND ADMINISTRATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eTake one tablet twice daily with morning and evening meals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eAlways take it with food to minimize gastrointestinal effects from the metformin component.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eSwallow whole with a full glass of water; do not crush or split.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eEscalation to higher-strength combinations can be made based on glycemic response and tolerability as directed by your physician.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eAssess eGFR before initiating and monitor renal function periodically throughout treatment.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSIDE EFFECTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eCommon: Genital mycotic infections, urinary tract infections, mild gastrointestinal discomfort during initiation, and increased urinary frequency.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-left: .5in; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eLess common: Volume depletion symptoms, including dizziness and mild blood pressure reduction, headache, and nasopharyngitis.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eNOT RECOMMENDED IN\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eContraindicated in type 1 diabetes and diabetic ketoacidosis. Not for use in patients with eGFR below 45ml\/min\/1.73m², severe hepatic impairment, excessive alcohol consumption, decompensated heart failure, respiratory failure, or during pregnancy and breastfeeding. Withhold temporarily before iodinated contrast imaging and during acute serious illness with significant dehydration risk.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDRUG INTERACTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eInsulin and sulfonylureas increase the risk when combined with this product. Diuretics potentiate the volume-depleting effect of empagliflozin. Iodinated contrast procedures require metformin discontinuation at least 48 hours before and after. UGT inducers such as rifampicin may reduce empagliflozin exposure. Cationic drugs such as cimetidine may elevate metformin levels through competition for renal tubular secretion.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSTORAGE INSTRUCTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eStore below 30°C in a cool, dry place away from moisture and direct sunlight. Keep in original blister packaging. Store out of reach of children. Do not use after the expiry date printed on the pack.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eWHERE TO BUY\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eDawa Healthcare Pharmacy provides a convenient and dependable platform for patients looking to buy Xenglu Met 5mg+500mg Tab 14s online in Pakistan, with genuine Hilton Pharma empagliflozin-metformin available from our verified supply chain. Patients looking up the Xenglu Met 5+500mg tablets 14s price in Pakistan will find accurate and current pricing at dawahealthcare.biz. Full details on Xenglu Met 5mg+500mg tab uses are available on our product page. Order online for same-day delivery throughout Karachi or fast nationwide courier delivery to any city in Pakistan. Dawa Healthcare Pharmacy's WhatsApp team and multiple branches of Karachi are available for medication support and queries.\u003c\/span\u003e\u003c\/p\u003e","brand":"Dawa Healthcare","offers":[{"title":"Pack","offer_id":51629450625307,"sku":"14920","price":418.5,"currency_code":"PKR","in_stock":true},{"title":"Strip","offer_id":51629450658075,"sku":"14920-1","price":209.3,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/placeholder_720x_ffb2071e-7930-43c2-a8cf-3bb1816b13c7.jpg?v=1768418065","url":"https:\/\/dawahealthcare.biz\/products\/xenglu-met-5mg-500mg-tab-14s","provider":"Dawa Healthcare","version":"1.0","type":"link"}