{"title":"Tramadol50mg","description":null,"products":[{"product_id":"tramal-50mg-cap","title":"TRAMAL 50MG CAP","description":"\u003ch1 dir=\"ltr\"\u003e\u003cspan\u003eTRAMAL 50MG CAP Online At The Best Price in Pakistan\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eGeneric:\u003c\/span\u003e\u003cspan\u003e Tramadol Hydrochloride\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eManufacturer:\u003c\/span\u003e\u003cspan\u003e Searle Pharma\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\n\u003cspan\u003eIndication:\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eTRAMAL 50MG CAP is an \u003c\/span\u003e\u003cspan\u003eopioid analgesic\u003c\/span\u003e\u003cspan\u003e used for the treatment of \u003c\/span\u003e\u003cspan\u003emoderate to moderately severe pain\u003c\/span\u003e\u003cspan\u003e. It works by binding to opioid receptors in the brain and altering how the body perceives and responds to pain signals. This medicine is prescribed in cases of \u003c\/span\u003e\u003cspan\u003epost-surgical pain\u003c\/span\u003e\u003cspan\u003e, \u003c\/span\u003e\u003cspan\u003echronic pain syndromes\u003c\/span\u003e\u003cspan\u003e, \u003c\/span\u003e\u003cspan\u003ecancer-related pain\u003c\/span\u003e\u003cspan\u003e, and severe musculoskeletal conditions that do not respond to standard painkillers. It is also considered for \u003c\/span\u003e\u003cspan\u003eneuropathic pain relief\u003c\/span\u003e\u003cspan\u003e due to its unique dual mechanism of action. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eAdministration:\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eTake orally with water, with or without food.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eUsual dose: 50mg every 4–6 hours as needed.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDo not exceed the prescribed daily maximum.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eShould be used strictly under medical supervision due to risk of dependence.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eSide Effects:\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eCommon:\u003c\/span\u003e\u003cspan\u003e Dizziness, nausea, constipation, headache, drowsiness.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eLess common:\u003c\/span\u003e\u003cspan\u003e Seizures, hallucinations, mood changes, difficulty breathing, allergic reactions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eAvailability:\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eTRAMAL 50MG CAP is available at leading medical stores and pharmacies across Pakistan. Patients can easily \u003c\/span\u003e\u003cspan\u003ebuy TRAMAL 50MG CAP online in Pakistan\u003c\/span\u003e\u003cspan\u003e through trusted sources. The \u003c\/span\u003e\u003cspan\u003eTRAMAL 50MG CAP price in Pakistan\u003c\/span\u003e\u003cspan\u003e is competitive and varies by brand and region. Customers can conveniently \u003c\/span\u003e\u003cspan\u003eorder TRAMAL 50MG CAP online\u003c\/span\u003e\u003cspan\u003e through Dawa Healthcare Pharmacy with confidence in authenticity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWith \u003c\/span\u003e\u003cspan\u003esame-day delivery in Karachi\u003c\/span\u003e\u003cspan\u003e, patients can receive their pain medication without delays. Dawa Healthcare Pharmacy, known as an \u003c\/span\u003e\u003ca href=\"https:\/\/dawahealthcare.biz\/\"\u003e\u003cstrong\u003eaffordable pharmacy in Karachi\u003c\/strong\u003e\u003c\/a\u003e\u003cspan\u003e, ensures genuine medicines, fast service, and professional support for effective pain management.\u003c\/span\u003e\u003c\/p\u003e","brand":"SEARLE PHARMA","offers":[{"title":"Strip","offer_id":47052806586651,"sku":"2370-1517","price":237.5,"currency_code":"PKR","in_stock":true},{"title":"Pack","offer_id":47163991458075,"sku":"2370-1518","price":237.5,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/products\/TRAMAL-50MG-CAP.jpg?v=1697641488"},{"product_id":"ramol-50mg-cap","title":"RAMOL 50MG CAP","description":"\u003cstrong\u003eGeneric Formula:  \u003c\/strong\u003eTramadol 50mg\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eMACTER INTERNATIONAL LIMITED","brand":"MACTER INTERNATIONAL LIMITED","offers":[{"title":"Strip","offer_id":47132530737435,"sku":"1356-949","price":0.0,"currency_code":"PKR","in_stock":false},{"title":"Pack","offer_id":47163967471899,"sku":"1356-950","price":0.0,"currency_code":"PKR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/products\/RAMOL-50MG-CAP.jpg?v=1706312963"},{"product_id":"tonoflex-50mg-cap","title":"TONOFLEX 50MG CAP","description":"\u003cstrong\u003eGeneric Formula:  \u003c\/strong\u003eTramadol 50mg\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eSAMI PHARMA","brand":"SAMI PHARMA","offers":[{"title":"Strip","offer_id":47056365682971,"sku":"1604-1019","price":251.8,"currency_code":"PKR","in_stock":true},{"title":"Pack","offer_id":47163968880923,"sku":"1604-1020","price":251.8,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/tonoflex_2050mg.webp?v=1705937085"},{"product_id":"pantra-50mg-inj","title":"PANTRA 50MG INJ","description":"\u003cstrong\u003eGeneric Formula:  \u003c\/strong\u003eTramadol 50mg\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eGETZ PHARMA","brand":"GETZ PHARMA","offers":[{"title":"Pack","offer_id":47093604057371,"sku":"6585-3491","price":0.0,"currency_code":"PKR","in_stock":false},{"title":"Unit","offer_id":47164081504539,"sku":"6585-3492","price":0.0,"currency_code":"PKR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/products\/PANTRA-50MG-INJ.jpg?v=1706020442"},{"product_id":"votadol-50mg-cap","title":"VOTADOL 50MG CAP","description":"\u003ch1\u003eVOTADOL 50MG CAPSULE ONLINE AT BEST PRICE IN PAKISTAN\u003c\/h1\u003e\n\u003ch3\u003e\n\u003cb\u003eGENERIC: \u003c\/b\u003eTramadol Hydrochloride 50mg\u003c\/h3\u003e\n\u003ch3\u003e\n\u003cb\u003eMANUFACTURER:\u003c\/b\u003e Horizon Pharmaceuticals (Pvt) Ltd\u003c\/h3\u003e\n\u003ch3\u003e\u003cb\u003eQUANTITY:\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003ePack of 30 capsules\u003c\/p\u003e\n\u003ch2\u003eINDICATION\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eVotadol 50mg Cap is a centrally acting opioid analgesic indicated for the treatment of moderate to moderately severe acute and chronic pain. It is used in post-operative pain, musculoskeletal pain, neuropathic pain, cancer pain, and other conditions where non-opioid analgesics provide insufficient pain relief.\u003c\/p\u003e\n\u003ch2\u003eMECHANISM OF ACTION\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eTramadol has a dual mechanism of action. It is a weak mu-opioid receptor agonist, providing analgesic activity through opioid pathways, including reduction of pain transmission in the spinal cord and brain. In addition, tramadol inhibits the neuronal reuptake of both serotonin and norepinephrine, enhancing descending inhibitory pain pathways independently of opioid receptors. This noradrenergic and serotonergic component contributes significantly to its analgesic effect, particularly in neuropathic pain. The active metabolite O-desmethyltramadol (M1), formed via CYP2D6, has approximately 200 times higher mu-opioid receptor affinity than the parent compound and is responsible for a substantial portion of the opioid analgesia.\u003c\/p\u003e\n\u003ch2\u003eDOSAGE AND ADMINISTRATION\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAdults: 50mg to 100mg every 4 to 6 hours as needed; maximum 400mg per day\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eElderly patients and those with renal or hepatic impairment: start at 50mg and extend dosing intervals\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eTake with or without food; swallow whole with water\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAlways follow the dosage prescribed by your doctor; use the lowest effective dose for the shortest duration\u003c\/p\u003e\n\u003ch2\u003eSIDE EFFECTS\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 4.0pt;\"\u003e\u003cb\u003eCommon:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eNausea and vomiting (most common, particularly on initiation)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eDizziness and somnolence\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eConstipation\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eHeadache and dry mouth\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 4.0pt;\"\u003e\u003cb\u003eLess common:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eSerotonin syndrome when combined with other serotonergic drugs (potentially serious)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eSeizures, particularly at high doses or in patients with predisposing risk factors\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eDependence and withdrawal syndrome with prolonged use; taper dose gradually on discontinuation\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eRespiratory depression at very high doses or in combination with CNS depressants\u003c\/p\u003e\n\u003ch2\u003eNOT RECOMMENDED IN\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAcute intoxication with alcohol, opioids, hypnotics, or psychotropic drugs\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eConcurrent or recent (within 14 days) use of MAO inhibitors (serotonin syndrome and seizure risk)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eSevere renal impairment (CrCl below 10 ml\/min) or severe hepatic impairment\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eKnown hypersensitivity to tramadol or opioids; epilepsy not adequately controlled; pregnancy and breastfeeding\u003c\/p\u003e\n\u003ch2\u003eDRUG INTERACTIONS\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eMAO inhibitors are contraindicated within 14 days of tramadol use due to the risk of life-threatening serotonin syndrome and seizures. Concurrent serotonergic drugs including SSRIs, SNRIs, triptans, linezolid, and St John's Wort significantly increase serotonin syndrome risk. CYP2D6 inhibitors such as fluoxetine and paroxetine reduce conversion of tramadol to its active M1 metabolite, potentially reducing analgesic efficacy while increasing serotonin-related side effects from the parent compound. CNS depressants including opioids, benzodiazepines, and alcohol produce additive respiratory depression and sedation; avoid combination. Carbamazepine induces tramadol metabolism, reducing plasma levels and analgesic efficacy.\u003c\/p\u003e\n\u003ch2\u003eSTORAGE INSTRUCTIONS\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eStore below 25°C in a dry place away from direct sunlight and moisture. Keep in original packaging. Keep out of reach of children. This medicine contains an opioid; store securely to prevent misuse.\u003c\/p\u003e\n\u003ch2\u003eWHERE TO BUY\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eYou can buy Votadol 50mg cap online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Votadol 50mg cap price in pakistan and learn about Votadol 50mg capsule uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Votadol 50mg capsule uses, pricing, and order placement.\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e \u003c\/p\u003e","brand":"HORIZON PHARMA","offers":[{"title":"Pack","offer_id":49828316971291,"sku":"13518","price":532.0,"currency_code":"PKR","in_stock":true},{"title":"Strip","offer_id":49828317004059,"sku":"13518-1","price":177.3,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/VOTADOL50MGCAP.jpg?v=1754502790"}],"url":"https:\/\/dawahealthcare.biz\/collections\/tramadol50mg.oembed","provider":"Dawa Healthcare","version":"1.0","type":"link"}