{"title":"Topiramate25mg","description":null,"products":[{"product_id":"hitop-25mg-tab","title":"HITOP 25MG TAB","description":"\u003cstrong\u003eGeneric Formula:  \u003c\/strong\u003eTopiramate 25mg\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eHILTON PHARMA","brand":"HILTON PHARMA","offers":[{"title":"Strip","offer_id":47132542796059,"sku":"5199-2749","price":337.9,"currency_code":"PKR","in_stock":false},{"title":"Pack","offer_id":47164048933147,"sku":"5199-2750","price":1013.7,"currency_code":"PKR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/04036.webp?v=1706744741"},{"product_id":"topirama-25mg-tab","title":"TOPIRAMA 25MG TAB","description":"\u003ch1 dir=\"ltr\"\u003e\u003cspan data-sheets-root=\"1\"\u003eBuy Topirama 25mg Tab Online At The Best Price In Pakistan\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp dir=\"ltr\"\u003eGeneric: Topiramate\u003cbr\u003eManufacturer: Platinum Pharmaceuticals\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eIndication:\u003cbr\u003eTOPIRAMA 25MG is used for the treatment of epilepsy and helps prevent seizures by stabilizing electrical activity in the brain. It is also prescribed for migraine prophylaxis, reducing the frequency and severity of attacks. This medicine may be used alone or with other antiepileptic drugs depending on patient needs. It supports long-term control of neurological symptoms for improved daily functioning. \u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003eAdministration:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003eTake exactly as prescribed by your doctor.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003eMay be taken with or without meals.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003eDo not skip doses or suddenly stop taking the medicine.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003eDrink plenty of water to reduce risk of kidney stones.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"ltr\"\u003eSide Effects:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003eCommon: Drowsiness, dizziness, tingling sensation, weight loss, mood changes.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003eLess Common: Vision problems, confusion, difficulty concentrating, kidney stones.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eAvailability:\u003cbr\u003e\n\u003c\/h3\u003e\n\u003cp\u003eYou can easily buy TOPIRAMA 25mg Tab online in Pakistan with reliable service. Check the TOPIRAMA 25mg Tab price in Pakistan before ordering. Customers can conveniently order TOPIRAMA 25mg Tab online from anywhere. We provide same-day delivery in Karachi. Trust Dawa Healthcare and \u003ca href=\"https:\/\/dawahealthcare.biz\/\"\u003eDawa Healthcare Pharmacy\u003c\/a\u003e for reliable service, authentic medicines, and timely delivery across Pakistan. Choose us for a seamless online pharmacy experience with guaranteed satisfaction.\u003cbr\u003e\u003c\/p\u003e","brand":"PLATINIUM PHARMACEUTICALS (PVT)","offers":[{"title":"Strip","offer_id":47056238805275,"sku":"4949-2669","price":229.0,"currency_code":"PKR","in_stock":true},{"title":"Pack","offer_id":47164043559195,"sku":"4949-2670","price":457.9,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/Topirama-Tablets-25mg-2X10s_44_11zon.jpg?v=1705936509"},{"product_id":"topagen-25mg-tab","title":"TOPAGEN 25MG TAB","description":"\u003cstrong\u003eGeneric Formula:  \u003c\/strong\u003eTopiramate 25mg\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eGENETICS PHARMA","brand":"GENETICS PHARMA","offers":[{"title":"Strip","offer_id":47093590130971,"sku":"4705-2455","price":337.3,"currency_code":"PKR","in_stock":true},{"title":"Pack","offer_id":47164035268891,"sku":"4705-2456","price":2023.5,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/topagen-25mg.webp?v=1705936591"},{"product_id":"topival-25mg-tab","title":"TOPIVAL 25MG TAB","description":"\u003ch1\u003eTOPIVAL 25MG TABLET ONLINE AT BEST PRICE IN PAKISTAN\u003c\/h1\u003e\n\u003ch3\u003e\n\u003cb\u003eGENERIC: \u003c\/b\u003eTopiramate 25mg\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cb\u003eMANUFACTURER:\u003c\/b\u003e Nectar Pharmaceuticals\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cb\u003eQUANTITY:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003ePack of 60 tablets\u003c\/p\u003e\n\u003ch2\u003eINDICATION\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eTopival 25mg Tab is a broad-spectrum anticonvulsant indicated as monotherapy or adjunctive therapy for partial-onset seizures with or without secondary generalization, and for primary generalized tonic-clonic seizures in adults and children. It is also indicated for the prevention of migraine headaches in adults.\u003c\/p\u003e\n\u003ch2\u003eMECHANISM OF ACTION\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eTopiramate has multiple complementary mechanisms. It blocks voltage-gated sodium channels, preventing the rapid repetitive firing of neurons that generates seizures. It enhances GABA-A receptor activity, increasing inhibitory neurotransmission. It antagonizes AMPA and kainite subtypes of glutamate receptors, reducing excitatory neurotransmission. It also weakly inhibits carbonic anhydrase, which may contribute to its anticonvulsant activity. The combination of these mechanisms provides broad-spectrum anticonvulsant activity. The 25mg dose is the standard starting and titration dose, taken once or twice daily.\u003c\/p\u003e\n\u003ch2\u003eDOSAGE AND ADMINISTRATION\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eEpilepsy (monotherapy): start 25mg once daily at night; increase by 25 to 50mg per week to 200 to 400mg\/day in divided doses\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eMigraine prophylaxis: 25mg once daily at night; increase weekly to 50mg twice daily\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAdjunctive therapy: titrate more slowly from 25mg per day\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAlways follow the titration schedule prescribed by your neurologist; never stop abruptly\u003c\/p\u003e\n\u003ch2\u003eSIDE EFFECTS\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 4.0pt;\"\u003e\u003cb\u003eCommon:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eSomnolence and cognitive slowing (word-finding difficulties, concentration problems)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eDizziness and ataxia\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eParesthesia (tingling in extremities; common and usually benign)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAnorexia and weight loss\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 4.0pt;\"\u003e\u003cb\u003eLess common:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eMetabolic acidosis with elevated blood ammonia\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eKidney stones (drink plenty of water to minimize risk)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAcute myopia and secondary angle-closure glaucoma (seek immediate attention if sudden vision change or eye pain)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eHyperthermia and reduced sweating, especially in children; monitor in hot weather\u003c\/p\u003e\n\u003ch2\u003eNOT RECOMMENDED IN\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eKnown hypersensitivity to topiramate\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eMetabolic acidosis with concurrent metformin (may worsen acidosis)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003ePregnancy: associated with increased risk of cleft lip and palate; use reliable contraception\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAvoid combined oral contraceptives at doses above 200mg\/day (reduces contraceptive efficacy)\u003c\/p\u003e\n\u003ch2\u003eDRUG INTERACTIONS\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eTopiramate reduces the efficacy of estrogen-containing oral contraceptives at doses above 200mg\/day; alternative contraception is required. Valproic acid combined with topiramate increases the risk of hyperammonemia and encephalopathy; monitor ammonia levels. CNS depressants and alcohol add to cognitive impairment and sedation. Carbonic anhydrase inhibitors such as acetazolamide combined with topiramate increase kidney stone risk. Phenytoin and carbamazepine reduce topiramate plasma levels.\u003c\/p\u003e\n\u003ch2\u003eSTORAGE INSTRUCTIONS\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eStore below 25°C in a dry place away from direct sunlight and moisture. Keep in original blister packaging. Keep out of reach of children.\u003c\/p\u003e\n\u003ch2\u003eWHERE TO BUY\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eYou can buy Topival 25mg Tab online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Topival 25mg tab price in pakistan and learn about Topival 25mg tab uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Topival 25mg tab uses, pricing, and order placement.\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e \u003c\/p\u003e","brand":"SWISS PHARMACEUTICALS","offers":[{"title":"Strip","offer_id":47393334198555,"sku":"12028-39","price":120.0,"currency_code":"PKR","in_stock":true},{"title":"Pack","offer_id":47393334231323,"sku":"12028-143","price":720.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/TOPIVAL_2025MG_20TAB_20_10.png?v=1701850859"}],"url":"https:\/\/dawahealthcare.biz\/collections\/topiramate25mg.oembed","provider":"Dawa Healthcare","version":"1.0","type":"link"}