{"title":"Resmetirom100mg","description":null,"products":[{"product_id":"restiro-100mg-tab","title":"RESTIRO 100MG TAB","description":"\u003ch1\u003e\u003cspan lang=\"EN-GB\"\u003eRestiro 100mg Tablets Online At Best Price In Pakistan\u003c\/span\u003e\u003c\/h1\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eGeneric: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eResmetirom 100mg\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eManufacturer: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eHorizon Pharmaceuticals (Pvt.) Ltd.\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eQuantity: \u003c\/span\u003e\u003c\/b\u003e\u003c\/h3\u003e\n\u003ch3\u003e\u003cspan lang=\"EN-GB\"\u003e10 Tablets\u003c\/span\u003e\u003c\/h3\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eINDICATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eRestiro 100mg Tab is prescribed for adult patients with non-alcoholic steatohepatitis (NASH) accompanied by moderate to advanced liver fibrosis (F2 to F3 stages), as an adjunct to dietary modifications and physical activity. NASH is a serious liver condition driven by excess fat accumulation, chronic inflammation, and progressive scarring of the liver. Restiro targets the metabolic root cause of this disease, working to reduce hepatic fat content, ease liver inflammation, and reverse early-stage fibrosis. It is particularly suited for patients weighing 100kg or more who require a higher therapeutic dose for effective disease management.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eMECHANISM OF ACTION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eResmetirom, the active ingredient in Restiro, selectively binds to the thyroid hormone receptor-beta in the liver. This receptor controls how liver cells manage fat. When activated, it boosts the liver's ability to break down stored fat, reduces the creation of new fat molecules, and lowers triglyceride levels within liver tissue. Think of it as switching on the liver's fat-burning engine. This targeted action reduces the fat overload that causes NASH-related inflammation and scarring, helping restore healthier liver function over time.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDOSAGE AND ADMINISTRATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eRecommended dose for patients weighing 100kg or more: 100mg once daily, taken orally.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eLower doses (60mg or 80mg) may apply for patients under 100kg; follow the physician's guidance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eMay be taken with or without food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eSwallow the tablet whole; do not crush, break, or chew.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eAdminister at the same time daily for best therapeutic results.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSIDE EFFECTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eCommon: Nausea, diarrhea, abdominal pain, vomiting.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eLess common: Dizziness, itching, gallbladder-related complications, raised liver enzymes.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eNOT RECOMMENDED IN\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eRestiro 100mg Tab is not recommended in patients with decompensated cirrhosis or those with known allergy to resmetirom. Patients with a history of gallbladder disease require close monitoring during treatment. This medicine is not suitable for use during pregnancy or breastfeeding without the explicit recommendation of a specialist. It should be used with caution in patients with moderate hepatic impairment, and liver function tests should be monitored regularly throughout the course of therapy.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDRUG INTERACTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eResmetirom can interact with statin medications, increasing the risk of muscle damage such as myopathy or rhabdomyolysis. Close monitoring for muscle pain and creatine kinase levels is advised. Co-administration with gemfibrozil or cyclosporine is not recommended due to significant pharmacokinetic interactions. Hepatic transporter substrates such as OATP1B1 and OATP1B3 drugs may also be affected. Patients should inform their doctor of all current medicines before starting Restiro.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSTORAGE INSTRUCTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eStore at room temperature (20°C to 25°C). Protect from direct sunlight, heat, and moisture. Keep in the original sealed packaging. Keep away from children. Do not use if the expiry date on the pack has passed.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eWHERE TO BUY\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003ePatients across Pakistan can conveniently buy Restiro 100mg Tab online in Pakistan through Dawa Healthcare Pharmacy, a trusted and licensed pharmaceutical platform. For those looking up the Restiro 100mg tablets price in Pakistan, our website provides reliable and up-to-date pricing information. You can order Restiro 100mg Tab online with confidence, and if you are located in Karachi, you can benefit from our same-day delivery service. For all other locations, we deliver through dependable courier services to every corner of Pakistan. Visit any of our multiple Karachi branches or reach us on WhatsApp for personalized support.\u003c\/span\u003e\u003c\/p\u003e","brand":"Dawa Healthcare","offers":[{"title":"Pack","offer_id":51065188188443,"sku":"14653","price":1520.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/RESTIRO_100MG_TAB.avif?v=1766312168"}],"url":"https:\/\/dawahealthcare.biz\/collections\/resmetirom100mg.oembed","provider":"Dawa Healthcare","version":"1.0","type":"link"}