{"title":"Oxcarbazipine600mg","description":null,"products":[{"product_id":"telox-600mg-tab","title":"TELOX 600MG TAB","description":"\u003cstrong\u003eGeneric Formula:  \u003c\/strong\u003eOxcarbazipine 600mg\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003ePLATINIUM PHARMACEUTICALS (PVT)","brand":"PLATINIUM PHARMACEUTICALS (PVT)","offers":[{"title":"Strip","offer_id":47056237461787,"sku":"4947-2667","price":568.1,"currency_code":"PKR","in_stock":true},{"title":"Pack","offer_id":47164043526427,"sku":"4947-2668","price":2840.5,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/products\/TELOX-600MG-TAB.jpg?v=1697639171"},{"product_id":"trioptal-600mg-tab","title":"TRIOPTAL 600MG TAB","description":"\u003ch1\u003e\u003cspan style=\"mso-ansi-language: EN-US;\"\u003eTrioptal 600mg Tablets Online At Best Price In Pakistan\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 8.0pt; line-height: normal;\"\u003e\u003cb\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e \u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eGeneric: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eOxcarbazepine 600mg\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eManufacturer: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003eNovartis Pharma Pakistan\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003cb\u003e\u003cspan lang=\"EN-GB\"\u003eQuantity: \u003c\/span\u003e\u003c\/b\u003e\u003cspan lang=\"EN-GB\"\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\u003cspan lang=\"EN-GB\"\u003e50 tablets per pack\u003c\/span\u003e\u003c\/h3\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eINDICATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eTrioptal 600mg Tab is an antiepileptic medication indicated for the treatment of partial-onset seizures (also called focal seizures) with or without secondary generalization in adults and children aged six years and above. It is used both as monotherapy in newly diagnosed epilepsy and as adjunctive therapy when additional seizure control is required in patients not fully controlled on existing antiepileptic regimens. It may also be used in the management of trigeminal neuralgia in some cases. Trioptal 600mg significantly reduces the frequency and severity of seizures, helping patients achieve better epilepsy control and improved quality of life.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eMECHANISM OF ACTION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal; margin: 12.0pt 0in 12.0pt 0in;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eOxcarbazepine works primarily by blocking voltage-gated sodium channels in brain neurons. These channels are responsible for generating the electrical signals (action potentials) that neurons use to communicate. In epilepsy, neurons fire excessively and repetitively, causing seizures. By stabilizing sodium channels in their inactive state, oxcarbazepine prevents rapid, high-frequency neuronal firing and reduces abnormal electrical activity in the brain. It also inhibits the release of glutamate, an excitatory neurotransmitter that promotes seizure propagation. Oxcarbazepine is a prodrug that is converted in the body into its active form, the monohydroxy derivative (MHD), which produces these effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDOSAGE AND ADMINISTRATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eAdults (monotherapy): Starting dose 300mg twice daily, increasing by up to 600mg per week to a usual maintenance of 1200mg per day.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eAdults (adjunctive therapy): Starting dose 300mg twice daily, with gradual increases to up to 2400mg per day as tolerated.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eDo not stop abruptly; always taper under physician supervision to avoid seizure rebound.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSIDE EFFECTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eCommon: Dizziness, somnolence, headache, nausea, diplopia (double vision), fatigue.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 3.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eLess common: Hyponatremia (low sodium), ataxia, tremor, vomiting, skin rash, Stevens-Johnson syndrome (rare but serious).\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eNOT RECOMMENDED IN\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eTrioptal 600mg Tab is not recommended in patients with known hypersensitivity to oxcarbazepine or carbamazepine, as significant cross-reactivity exists. Hyponatremia is a serious risk; sodium levels should be monitored, particularly in elderly patients and those on diuretics or other sodium-depleting medications. Not suitable for patients with severe hepatic impairment. Use during pregnancy requires specialist evaluation, as oxcarbazepine may increase the risk of fetal malformations; effective contraception is essential for women of childbearing potential.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eDRUG INTERACTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eOxcarbazepine is a significant inducer of CYP3A4 and reduces the plasma levels of oral contraceptives, making them less effective; alternative contraception is essential. It lowers the efficacy of other CYP3A4-metabolized drugs, including some antiepileptics, immunosuppressants, and calcium channel blockers. CYP2C19 inhibitors, including felodipine and verapami,l may increase oxcarbazepine levels. Combination with diuretics, NSAIDs, or other medications that lower sodium increases the risk of hyponatremia. Other antiepileptd.ics may interact to alter plasma concentrations; regular drug level monitoring may be require\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eSTORAGE INSTRUCTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt; line-height: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eStore in a cool, dry place below 30°C. Protect from direct sunlight and moisture. Keep in original packaging. Store out of reach of children. Do not use after the expiry date printed on the carton.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan lang=\"EN-GB\"\u003eWHERE TO BUY\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: normal; margin: 12.0pt 0in 12.0pt 0in;\"\u003e\u003cspan lang=\"EN-GB\" style=\"font-size: 14.0pt;\"\u003eDawa Healthcare Pharmacy provides epilepsy patients across Pakistan with dependable access to Trioptal 600mg Tab online, ensuring the supply of genuine medication with prompt and professional delivery. Patients looking for the Trioptal 600mg tablets price in Pakistan can rely on our website for accurate and updated pricing information. You can order Trioptal 600mg Tab online and benefit from same day delivery within Karachi, while our nationwide courier network delivers to cities and towns across Pakistan. Our WhatsApp support and multiple branches in Karachi are available to assist with medication queries.\u003c\/span\u003e\u003c\/p\u003e","brand":"NOVARTIS PHARMA (PAK) LTD","offers":[{"title":"Pack","offer_id":49828313563419,"sku":"13495","price":3080.0,"currency_code":"PKR","in_stock":false},{"title":"Strip","offer_id":49828313596187,"sku":"13495-1","price":616.0,"currency_code":"PKR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/TRIOPTAL600MGTAB.jpg?v=1754502503"}],"url":"https:\/\/dawahealthcare.biz\/collections\/oxcarbazipine600mg.oembed","provider":"Dawa Healthcare","version":"1.0","type":"link"}