{"title":"Desvenlafaxine50mg","description":null,"products":[{"product_id":"denla-xr-50mg-tab","title":"DENLA XR 50MG TAB","description":"\u003ch1\u003eDENLA XR 50MG TABLET ONLINE AT BEST PRICE IN PAKISTAN\u003c\/h1\u003e\n\u003ch3\u003e\n\u003cspan style=\"font-size: 14.0pt;\"\u003eGENERIC: \u003c\/span\u003e\u003cspan style=\"font-size: 14.0pt; font-weight: normal;\"\u003eDesvenlafaxine 50mg (Extended Release)\u003c\/span\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\n\u003cspan style=\"font-size: 14.0pt;\"\u003eMANUFACTURER: \u003c\/span\u003e\u003cspan style=\"font-size: 14.0pt; font-weight: normal;\"\u003eSemos Pharma\u003c\/span\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003ch3\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eQUANTITY: \u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003ePack of 14 tablets\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eINDICATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eDenla XR 50mg Tab is a serotonin-norepinephrine reuptake inhibitor (SNRI) approved for the treatment of major depressive disorder (MDD) in adults. It is the active metabolite of venlafaxine and provides consistent therapeutic levels with once-daily dosing due to its extended-release formulation.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eMECHANISM OF ACTION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eDesvenlafaxine is a potent inhibitor of serotonin and norepinephrine reuptake transporters (SERT and NET). By blocking reuptake, it increases the availability of serotonin and norepinephrine in the synaptic cleft, enhancing both monoaminergic systems involved in mood regulation. Unlike venlafaxine, desvenlafaxine is not significantly metabolized by CYP2D6, which reduces interindividual pharmacokinetic variability.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eDOSAGE AND ADMINISTRATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eRecommended dose: 50mg once daily at the same time each day\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eNo additional benefit demonstrated with doses above 50mg\/day in most patients\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eMay be taken with or without food\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eDo not discontinue abruptly; taper the dose gradually under medical supervision\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eSIDE EFFECTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin: 4.0pt 0in 3.0pt 0in;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eCommon:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eNausea (most common, especially in the first 2 weeks)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eHeadache, dizziness\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eDry mouth, constipation\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eInsomnia, excessive sweating\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin: 4.0pt 0in 3.0pt 0in;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eLess common:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eIncreased blood pressure and heart rate (monitor regularly)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eHyponatremia, especially in elderly patients\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eSerotonin syndrome when combined with other serotonergic agents\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eSuicidal ideation in young adults during initial treatment\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eNOT RECOMMENDED IN\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eConcurrent or recent use of MAOIs (allow 14 days after stopping an MAOI)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eUncontrolled narrow-angle glaucoma\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eKnown hypersensitivity to desvenlafaxine or venlafaxine\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eUse with caution in patients with hypertension, cardiovascular disease, or seizure disorder\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eDRUG INTERACTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eDesvenlafaxine should not be combined with MAOIs, linezolid, or IV methylene blue due to the risk of serotonin syndrome. It can increase the anticoagulant effect of warfarin; monitor INR. Concurrent use with NSAIDs, aspirin, or antiplatelet agents increases the risk of gastrointestinal bleeding.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eSTORAGE INSTRUCTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eStore Denla XR 50mg tablets at room temperature between 20°C and 25°C. Protect from moisture. Keep in original packaging. Store out of reach of children.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"mso-bidi-font-size: 14.0pt;\"\u003eWHERE TO BUY\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e\u003cspan style=\"font-size: 14.0pt;\"\u003eBuy Denla XR 50mg Tab online from Dawa Healthcare Pharmacy with a valid prescription. Check the Denla XR 50mg Tab price in Pakistan and get information on Denla XR 50mg Tab uses from our team. Same-day delivery in Karachi. Nationwide delivery available through Dawa Healthcare Pharmacy across Pakistan.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 12.0pt;\"\u003e \u003c\/p\u003e","brand":"AVANT PHARMA","offers":[{"title":"Strip","offer_id":47393311195419,"sku":"12218-79","price":280.7,"currency_code":"PKR","in_stock":true},{"title":"Pack","offer_id":47393311228187,"sku":"12218-183","price":561.5,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/Denla-Xr-50mg-Tablets.jpg?v=1707982288"}],"url":"https:\/\/dawahealthcare.biz\/collections\/desvenlafaxine50mg.oembed","provider":"Dawa Healthcare","version":"1.0","type":"link"}