{"title":"Amikacin100mg","description":null,"products":[{"product_id":"grasil-100mg-vial","title":"GRASIL 100MG VIAL","description":"\u003cstrong\u003eGeneric Formula:  \u003c\/strong\u003eAmikacin 100mg\u003cbr\u003e\u003cstrong\u003eManufacturer: \u003c\/strong\u003eSAMI PHARMA","brand":"SAMI PHARMA","offers":[{"title":"Default Title","offer_id":47056366928155,"sku":"1465","price":153.1,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/products\/GRASIL-100MG-VIAL_076fbc97-c265-4bc8-a7f7-e548d6cd152a.jpg?v=1706595401"},{"product_id":"amkay-100mg-2ml-inj","title":"AMKAY 100MG\/2ML INJ","description":"\u003ch1\u003eAMKAY 100MG\/2ML INJECTION ONLINE AT BEST PRICE IN PAKISTAN\u003c\/h1\u003e\n\u003ch3\u003e\n\u003cb\u003eGENERIC: \u003c\/b\u003eAmikacin Sulphate 100mg\/2ml\u003c\/h3\u003e\n\u003ch3\u003e\n\u003cb\u003eMANUFACTURER:\u003c\/b\u003e Bosch Pharmaceuticals\u003c\/h3\u003e\n\u003ch3\u003e\u003cb\u003eQUANTITY:\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e5 ampoules per pack\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eINDICATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eAmkay 100mg Inj is an aminoglycoside antibiotic indicated for the treatment of serious and life-threatening bacterial infections caused by susceptible gram-negative organisms including Pseudomonas aeruginosa, Escherichia coli, Klebsiella, Enterobacter, Serratia, Acinetobacter, and Staphylococcus aureus. It is particularly valuable in infections caused by organisms resistant to gentamicin and tobramycin. It is used in nosocomial pneumonia, urinary tract infections, septicemia, bacterial endocarditis, peritonitis, and bone and joint infections.\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eMECHANISM OF ACTION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eAmikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. It irreversibly binds to the 30S ribosomal subunit of susceptible bacteria, interfering with mRNA translation and causing misreading of the genetic code, resulting in production of non-functional proteins and bactericidal death. Its unique structural features make it resistant to most aminoglycoside-inactivating enzymes produced by resistant bacteria, retaining activity against many gentamicin and tobramycin-resistant gram-negative organisms. It is particularly valuable as a component of combination therapy for severe gram-negative infections.\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eDOSAGE AND ADMINISTRATION\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eAdults: 15mg\/kg\/day in 2 or 3 divided doses by IM or IV injection\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eChildren: 15 to 22.5mg\/kg\/day in 2 to 3 divided doses\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eNeonates: 7.5 to 10mg\/kg every 12 to 24 hours based on gestational and postnatal age\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eTherapeutic drug monitoring (peak and trough levels) is mandatory for safe and effective dosing; dose adjustment required in renal impairment\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eSIDE EFFECTS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 4.0pt;\"\u003e\u003cb\u003eCommon:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eNephrotoxicity: elevated creatinine and reduced urine output (monitor renal function daily)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eOtotoxicity: cochlear (hearing loss and tinnitus) and vestibular (dizziness, vertigo) damage\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eInjection site pain with intramuscular administration\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eNeuromuscular blockade at high doses\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 4.0pt;\"\u003e\u003cb\u003eLess common:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eIrreversible hearing loss with prolonged use or excessive plasma levels\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eRenal tubular necrosis with severe nephrotoxicity\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eHypersensitivity reactions including rash\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eHypomagnesaemia and hypokalaemia with prolonged therapy\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eNOT RECOMMENDED IN\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eKnown hypersensitivity to amikacin or other aminoglycosides (cross-sensitivity possible)\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003ePre-existing severe renal impairment without dose adjustment and monitoring\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eConcurrent use with other nephrotoxic or ototoxic agents without mandatory monitoring\u003c\/p\u003e\n\u003cp class=\"MsoListParagraph\" style=\"text-indent: -.25in; mso-list: l0 level1 lfo1; margin: 0in 0in 4.0pt .5in;\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e•\u003cspan style=\"font: 7.0pt 'Times New Roman';\"\u003e      \u003c\/span\u003e\u003c\/span\u003e\u003c!--[endif]--\u003eMyasthenia gravis (may exacerbate neuromuscular weakness)\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eDRUG INTERACTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eOther nephrotoxic agents including amphotericin B, vancomycin, and ciclosporin significantly increase nephrotoxicity risk; avoid or monitor intensively. Furosemide and other loop diuretics increase ototoxicity risk; avoid concurrent use. Neuromuscular blocking agents have potentiated effects with aminoglycosides; use with great caution in anaesthesia. NSAIDs reduce renal elimination of aminoglycosides. Cephalosporins are physically incompatible with aminoglycosides in the same syringe.\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eSTORAGE INSTRUCTIONS\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eStore at room temperature between 15°C and 30°C. Protect from light and heat. Do not freeze. Keep out of reach of children.\u003c\/p\u003e\n\u003ch2\u003e\u003cspan style=\"font-size: 16.0pt; mso-bidi-font-size: 14.0pt;\"\u003eWHERE TO BUY\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003eYou can buy Amkay 100mg\/2ml Injection online from Dawa Healthcare Pharmacy at dawahealthcare.biz, one of Pakistan's most trusted pharmacies for authentic, pharmacist-verified medicines. Browse our product page to check the current Amkay 100mg\/2ml Injection price in pakistan, read detailed clinical information, and place your order from the comfort of your home. Our experienced pharmacy team is always available to answer your questions about Amkay 100mg\/2ml Injection uses and correct dosage. Customers in Karachi enjoy same-day delivery on orders placed before the daily cutoff, while customers across Pakistan benefit from our nationwide courier service for safe and timely delivery to any city. You can also visit any of our Karachi branches in person or reach our dedicated WhatsApp support team for instant help with Amkay 100mg\/2ml Injection uses, pricing, prescriptions, and order placement.\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 6.0pt;\"\u003e \u003c\/p\u003e","brand":"BOSCH PHARMA","offers":[{"title":"Pack","offer_id":49828280533275,"sku":"13173","price":85.2,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0772\/8041\/1931\/files\/placeholder_720x_973361c2-48db-4842-96b0-22d43578ff8f.jpg?v=1736255404"}],"url":"https:\/\/dawahealthcare.biz\/collections\/amikacin100mg.oembed","provider":"Dawa Healthcare","version":"1.0","type":"link"}